Schizophrenia is a severely debilitating neurodevelopmental disorder. Establishing a
causal link between circuit dysfunction and particular behavioral traits that are relevant to …

Activation of G-protein-coupled receptors (GPCRs) results in a variety of cellular responses,
such as binding to the same receptor of different ligands that activate distinct downstream …

In various mental disorders, dysfunction of the prefrontal cortex contributes to cognitive deficits.
Here we studied how the claustrum (CLA), a nucleus sharing reciprocal connections with …

Parkinson’s disease (PD) patients suffer not only from the primary motor symptoms of the
disease but also from a range of non-motor symptoms (NMS) that cause disability and low …

Putative functions of the cellular prion protein, PrP C , include resistance to oxidative stress,
copper uptake, cell adhesion, and cell signaling. Here, we report NADPH oxidase-…

Adipose tissue dysfunction in obesity has been linked to low-grade inflammation causing
insulin resistance. Transcriptomic studies have identified death-associated protein kinase 2 (…

BACKGROUND AND AIMS: Glycogen storage disease type 1a (GSD1a) is an inherited
disease caused by a deficiency in the catalytic subunit of the glucose-6 phosphatase enzyme (…

A major determinant of neuronal homeostasis is the proper integration of cell signaling
pathways recruited by a variety of neuronal and non‐neuronal factors. By taking advantage of a …

Glycogen storage disease type 1a (GSD1a) is a rare disease due to the deficiency in the
glucose-6-phosphatase (G6Pase) catalytic subunit (encoded by G6pc), which is essential for …

The cellular prion protein PrP C is the normal counterpart of the scrapie prion protein PrP Sc
, the main component of the infectious agent of transmissible spongiform encephalopathies (…