User profiles for Stacey D. Finley
Stacey D. FinleyUniversity of Southern California Verified email at usc.edu Cited by 2155 |
A systems biology view of blood vessel growth and remodelling
Blood travels throughout the body in an extensive network of vessels – arteries, veins and
capillaries. This vascular network is not static, but instead dynamically remodels in response …
capillaries. This vascular network is not static, but instead dynamically remodels in response …
[HTML][HTML] The 2019 mathematical oncology roadmap
… Finley proposes a multiscale approach to modelling kinetics and time-varying heterogeneities
that may arise in aberrant cell metabolism in cancer due to environmental fluctuations. …
that may arise in aberrant cell metabolism in cancer due to environmental fluctuations. …
[HTML][HTML] In silico feasibility of novel biodegradation pathways for 1, 2, 4-trichlorobenzene
Background Bioremediation offers a promising pollution treatment method in the reduction
and elimination of man-made compounds in the environment. Computational tools to predict …
and elimination of man-made compounds in the environment. Computational tools to predict …
[PDF][PDF] Fund black scientists
Our nationwide network of BME women faculty collectively argue that racial funding disparity
by the National Institutes of Health (NIH) remains the most insidious barrier to success of …
by the National Institutes of Health (NIH) remains the most insidious barrier to success of …
Computational framework for predictive biodegradation
SD Finley, LJ Broadbelt… - Biotechnology and …, 2009 - Wiley Online Library
As increasing amounts of anthropogenic chemicals are released into the environment, it is
vital to human health and the preservation of ecosystems to evaluate the fate of these …
vital to human health and the preservation of ecosystems to evaluate the fate of these …
Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: systems biology predictions
Background Vascular endothelial growth factor (VEGF) is known to be a potent promoter of
angiogenesis under both physiological and pathological conditions. Given its role in …
angiogenesis under both physiological and pathological conditions. Given its role in …
[HTML][HTML] Multi-scale modeling of macrophage—T cell interactions within the tumor microenvironment
CG Cess, SD Finley - PLoS computational biology, 2020 - journals.plos.org
Within the tumor microenvironment, macrophages exist in an immunosuppressive state,
preventing T cells from eliminating the tumor. Due to this, research is focusing on …
preventing T cells from eliminating the tumor. Due to this, research is focusing on …
[HTML][HTML] ERK and Akt exhibit distinct signaling responses following stimulation by pro-angiogenic factors
Background Angiogenesis plays an important role in the survival of tissues, as blood vessels
provide oxygen and nutrients required by the resident cells. Thus, targeting angiogenesis is …
provide oxygen and nutrients required by the resident cells. Thus, targeting angiogenesis is …
[HTML][HTML] Calibrating agent-based models to tumor images using representation learning
CG Cess, SD Finley - PLOS Computational Biology, 2023 - journals.plos.org
Agent-based models (ABMs) have enabled great advances in the study of tumor development
and therapeutic response, allowing researchers to explore the spatiotemporal evolution of …
and therapeutic response, allowing researchers to explore the spatiotemporal evolution of …
Integrative approaches to cancer immunotherapy
Cancer immunotherapy aims to arm patients with cancer-fighting immunity. Many new
cancer-specific immunotherapeutic drugs have gained approval in the past several years, …
cancer-specific immunotherapeutic drugs have gained approval in the past several years, …