Laparoscopic Heller myotomy and Dor fundoplication

E McCarthy, SL Jao, AD Pryor - World Journal of Surgery, 2022 - Springer
Introduction Achalasia is an esophageal motility disorder characterized by disordered
esophageal peristalsis with failed relaxation of the lower esophageal sphincter resulting in a …

Opposing effects of an F-box protein and the HSP90 chaperone network on microtubule stability and neurite growth in Caenorhabditis elegans

C Zheng, E Atlas, HMT Lee, SLJ Jao… - …, 2020 - journals.biologists.com
Molecular chaperones often work collaboratively with the ubiquitylation-proteasome system
(UPS) to facilitate the degradation of misfolded proteins, which typically safeguards cellular …

Epistatic, synthetic, and balancing interactions among tubulin missense mutations affecting neurite growth in Caenorhabditis elegans

HMT Lee, NY Sayegh, AS Gayek, SLJ Jao… - Molecular Biology of …, 2021 - Am Soc Cell Biol
Mutations in tubulins affect microtubule (MT) dynamics and functions during neuronal
differentiation and their genetic interaction provides insights into the regulation of MT functions. We …

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

LE Jao, SR Wente, W Chen - Proceedings of the National …, 2013 - National Acad Sciences
A simple and robust method for targeted mutagenesis in zebrafish has long been sought.
Previous methods generate monoallelic mutations in the germ line of F0 animals, usually …

Deleterious mutations in the essential mRNA metabolism factor, hGle1, in amyotrophic lateral sclerosis

…, AW Folkmann, VV Belzil, LE Jao… - Human molecular …, 2015 - academic.oup.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by
the selective death of motor neurons. Causative mutations in the global RNA-processing …

A zebrafish model of lethal congenital contracture syndrome 1 reveals Gle1 function in spinal neural precursor survival and motor axon arborization

LE Jao, B Appel, SR Wente - Development, 2012 - journals.biologists.com
… μm in B,D,F,J; 100 μm in H,L and F inset; 50 μm in L inset. … 500 μm in B,D,F,J; 100 μm in H,L
and F inset; 50 μm in L inset. … : 500 μm in B,D,F,J; 100 μm in H,L and F inset; 50 μm in L inset. …

A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies

LE Jao, A Akef, SR Wente - Molecular biology of the cell, 2017 - Am Soc Cell Biol
Control of organellar assembly and function is critical to eukaryotic homeostasis and survival.
Gle1 is a highly conserved regulator of RNA-dependent DEAD-box ATPase proteins, with …

Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates

…, L Cheung, X Jiang, D Yoon, B Huang, LE Jao - Elife, 2018 - elifesciences.org
10.7554/eLife.34959.001 As microtubule-organizing centers of animal cells, centrosomes
guide the formation of the bipolar spindle that segregates chromosomes during mitosis. At …

[BOOK][B] Transdisciplinarity in mathematics education: Blurring disciplinary boundaries

L Jao, N Radakovic - 2017 - Springer
… To Susan Jagger, our friend and colleague, we are so appreciative of your friendship,
encouragement, and sense of humor. We also thank Barb, for her enthusiasm and positive energy. …

[PDF][PDF] Condensation of pericentrin proteins in human cells illuminates phase separation in centrosome assembly

…, L Jiang, S Yamada, LE Jao - Journal of cell …, 2021 - journals.biologists.com
… the Jao and Ho labs for discussion; Emily Jao for help with illustration of the model figure.
Experiments were performed in part through the use of Davis Campus Shared Flow Cytometry …