Elevated postprandial blood glucose levels constitute a global epidemic and a major risk
factor for prediabetes and type II diabetes, but existing dietary methods for controlling them …

Human gut microbiome composition is shaped by multiple factors but the relative contribution
of host genetics remains elusive. Here we examine genotype and microbiome data from …

Metagenomic sequencing increased our understanding of the role of the microbiome in
health and disease, yet it only provides a snapshot of a highly dynamic ecosystem. Here, we …

Bread is consumed daily by billions of people, yet evidence regarding its clinical effects is
contradicting. Here, we performed a randomized crossover trial of two 1-week-long dietary …

Colonic homeostasis entails epithelium-lymphocyte cooperation, yet many participants in
this process are unknown. We show here that epithelial microRNAs mediate the mucosa–…

Age-related macular degeneration (AMD) is the major cause of blindness in developed
nations. AMD is characterized by retinal pigmented epithelial (RPE) cell dysfunction and loss of …

microRNAs (miRNAs) are known to play an essential role in controlling a broad range of
biological processes including animal development. Accordingly, many miRNAs are expressed …

Precise gene expression patterns are established by transcription factor (TFs) binding to
regulatory sequences. While these events occur in the context of chromatin, our understanding …

MicroRNAs (miRNAs) are a class of small non-coding RNAs that play an important role in
mediating a broad and expanding range of biological activities. miR-375 is expressed …

MicroRNAs are transcribed by RNA polymerase II but the transcriptional features influencing
their synthesis are poorly defined. Here we report that a TATA box in microRNA and protein-…