[HTML][HTML] Mechanistic modeling quantifies the influence of tumor growth kinetics on the response to anti-angiogenic treatment

TD Gaddy, Q Wu, AD Arnheim… - PLoS computational …, 2017 - journals.plos.org
Tumors exploit angiogenesis, the formation of new blood vessels from pre-existing vasculature,
in order to obtain nutrients required for continued growth and proliferation. Targeting …

Aging alters the skeletal response to disuse in the rat

…, ER Siegel, LJ Suva, D Gaddy - American Journal …, 2007 - journals.physiology.org
Disuse has been shown to cause a rapid and dramatic loss of skeletal mass and strength in
the load-bearing bones of young and mature animals and humans. However, little is known …

Television's impact on high school achievement

GD Gaddy - Public opinion quarterly, 1986 - academic.oup.com
Using data from the first two waves of the High School and Beyond project, this study
examines the reciprocal relationship between media use and academic achievement among …

Matrix metalloproteinases in multiple myeloma

T Kelly, M Børset, E Abe, D Gaddy-Kurten… - Leukemia & …, 2000 - Taylor & Francis
Multiple myeloma is a deadly malignancy characterized by plasma cell infiltration of bones.
The resulting effect is painful “punched-out” lesions where bone is eroded and filled with …

[HTML][HTML] Osteopenia in a mouse model of spinal cord injury: Effects of age, Sex and Motor Function

…, R Cunningham, A Sefiani, K Callaway, D Gaddy… - Biology, 2022 - mdpi.com
Simple Summary In the first two years following spinal cord injury, people lose up to 50% of
bone below the injury. This injury-induced bone loss significantly affects rehabilitation and …

Synaptophysin immunoreactivity in the rat pituitary: alterations after 6-hydroxydopamine treatment

LC Saland, D Thomas, M Morales, J Gaddy - Endocrine, 1998 - Springer
Synaptophysin (SN) is a synaptic-vesicle-associated membrane protein whose presence is
indicative of intact, functional synapses. This study examines the presence of SN in pituitary …

Synaptophysin immunoreactivity in the aging rat pituitary gland

…, D Ramirez, V Hernandez, J Gaddy, D Thomas - Brain research …, 1997 - Elsevier
The density of synaptophysin (SN)-immunoreactivity (IR) was examined in pituitary glands
of aging male Sprague-Dawley rats. SN-IR was observed as dense dots among endocrine …

Regulation of bone mass by mechanical loading: microarchitecture and genetics

LJ Suva, D Gaddy, DS Perrien, RL Thomas… - Current osteoporosis …, 2005 - Springer
For decades, the processes that couple bone architecture and mass to function have been
investigated and characterized. It is well known, and now well accepted, that increases in …

Tumor-derived interleukin-8 stimulates osteolysis independent of the receptor activator of nuclear factor-κB ligand pathway

…, A Martinez, TA Guise, JM Chirgwin, D Gaddy… - Cancer research, 2005 - AACR
Bone is a common site of cancer metastasis. Breast, prostate, and lung cancers show a
predilection to metastasize to bone. Recently, we reported that the chemokine interleukin 8 (IL-8) …

Television as an Instrument in the Informal Education of Preschool Children: An Analysis of National Options.

GD Gaddy, FA Biocca - 1984 - ERIC
There are a number of ways that government policy might increase the educational benefits
that preschool children receive from television. These include (1) direct government funding …