Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini… - Nature, 2016 - nature.com
Mutations of the tricarboxylic acid cycle enzyme fumarate hydratase cause hereditary
leiomyomatosis and renal cell cancer 1 . Fumarate hydratase-deficient renal cancers are highly …
leiomyomatosis and renal cell cancer 1 . Fumarate hydratase-deficient renal cancers are highly …
The ATR Inhibitor AZD6738 Synergizes with Gemcitabine In Vitro and In Vivo to Induce Pancreatic Ductal Adenocarcinoma Regression
Y Wallez, CR Dunlop, TI Johnson, SB Koh… - Molecular cancer …, 2018 - AACR
Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest cancers, and overall
survival rates have barely improved over the past five decades. The antimetabolite gemcitabine …
survival rates have barely improved over the past five decades. The antimetabolite gemcitabine …
[HTML][HTML] Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models
CR Dunlop, Y Wallez, TI Johnson… - British journal of …, 2020 - nature.com
Background Personalised medicine strategies may improve outcomes in pancreatic ductal
adenocarcinoma (PDAC), but validation of predictive biomarkers is required. Having …
adenocarcinoma (PDAC), but validation of predictive biomarkers is required. Having …
[HTML][HTML] Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells
Deregulated signal transduction and energy metabolism are hallmarks of cancer and both
play a fundamental role in tumorigenesis. While it is increasingly recognised that signalling …
play a fundamental role in tumorigenesis. While it is increasingly recognised that signalling …
Physiological and pathological roles in human adrenal of the glomeruli-defining matrix protein NPNT (nephronectin)
AED Teo, S Garg, TI Johnson, W Zhao, J Zhou… - …, 2017 - Am Heart Assoc
Primary aldosteronism is a common cause of hypertension, which becomes refractory if
undiagnosed, but potentially curable when caused by an aldosterone-producing adenoma (APA)…
undiagnosed, but potentially curable when caused by an aldosterone-producing adenoma (APA)…
NEFM (neurofilament medium) polypeptide, a marker for zona glomerulosa cells in human adrenal, inhibits D1R (dopamine D1 receptor)–mediated secretion of …
C Maniero, S Garg, W Zhao, TI Johnson, J Zhou… - …, 2017 - Am Heart Assoc
Heterogeneity among aldosterone-producing adenomas (APAs) has been highlighted by the
discovery of somatic mutations. KCNJ5 mutations predominate in large zona fasciculata (ZF…
discovery of somatic mutations. KCNJ5 mutations predominate in large zona fasciculata (ZF…
Correction: Corrigendum: Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini… - Nature, 2016 - ideas.repec.org
… Marco Sciacovelli & Emanuel Gonçalves & Timothy Isaac Johnson & Vincent Roberto
Zecchini & Ana Sofia Henriques da Costa & Edoardo Gaude & Alizee Vercauteren Drubbel & …
Zecchini & Ana Sofia Henriques da Costa & Edoardo Gaude & Alizee Vercauteren Drubbel & …
Primary aldosteronism
C Maniero, S Garg, W Zhao, TI Johnson, J Zhou… - …, 2017 - Am Heart Assoc
Heterogeneity among aldosterone-producing adenomas (APAs) has been highlighted by the
discovery of somatic mutations. KCNJ5 mutations predominate in large zona fasciculata (ZF…
discovery of somatic mutations. KCNJ5 mutations predominate in large zona fasciculata (ZF…
Corrigendum to “Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells”[Metabol. Eng. 45 (2018) 149–157]
… Emanuel Gonçalves, a Marco Sciacovelli, b Ana SH Costa, b Maxine Gia Binh Tran, d
Timothy Isaac Johnson, b Daniel Machado, c, f Christian Frezza, b, ∗ and Julio Saez-Rodriguez …
Timothy Isaac Johnson, b Daniel Machado, c, f Christian Frezza, b, ∗ and Julio Saez-Rodriguez …
The effect of population and" structural" biases on social media-based algorithms: A case study in geolocation inference across the urban-rural spectrum
I Johnson, C McMahon, J Schöning… - Proceedings of the 2017 …, 2017 - dl.acm.org
Much research has shown that social media platforms have substantial population biases.
However, very little is known about how these population biases affect the many algorithms …
However, very little is known about how these population biases affect the many algorithms …