User profiles for Trent Northen

Trent R Northen

Lawrence Berkeley National Laboratory
Verified email at lbl.gov
Cited by 17251

Dynamic root exudate chemistry and microbial substrate preferences drive patterns in rhizosphere microbial community assembly

…, D Loqué, BP Bowen, MK Firestone, TR Northen… - Nature …, 2018 - nature.com
Like all higher organisms, plants have evolved in the context of a microbial world, shaping
both their evolution and their contemporary ecology. Interactions between plant roots and soil …

Feed your friends: do plant exudates shape the root microbiome?

J Sasse, E Martinoia, T Northen - Trends in plant science, 2018 - cell.com
Plant health in natural environments depends on interactions with complex and dynamic
communities comprising macro- and microorganisms. While many studies have provided …

[HTML][HTML] Probing the active fraction of soil microbiomes using BONCAT-FACS

…, R Chakraborty, RR Malmstrom, TR Northen - Nature …, 2019 - nature.com
The ability to link soil microbial diversity to soil processes requires technologies that
differentiate active microbes from extracellular DNA and dormant cells. Here, we use BONCAT (…

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

…, DJ Floros, RG Gavilan, K Kleigrewe, T Northen… - Nature …, 2016 - nature.com
The potential of the diverse chemistries present in natural products (NP) for biotechnology
and medicine remains untapped because NP databases are not searchable with raw data …

Clathrate nanostructures for mass spectrometry

TR Northen, O Yanes, MT Northen, D Marrinucci… - Nature, 2007 - nature.com
The ability of mass spectrometry to generate intact biomolecular ions efficiently in the gas
phase has led to its widespread application in metabolomics 1 , proteomics 2 , biological …

Deciphering microbial interactions in synthetic human gut microbiome communities

…, R Lau, BP Bowen, S Hromada, T Northen… - Molecular systems …, 2018 - embopress.org
The ecological forces that govern the assembly and stability of the human gut microbiota
remain unresolved. We developed a generalizable model‐guided framework to predict higher‐…

[HTML][HTML] Gut microbiota mediate caffeine detoxification in the primary insect pest of coffee

…, HC Lim, P Kosina, F Infante, TR Northen… - Nature …, 2015 - nature.com
The coffee berry borer (Hypothenemus hampei) is the most devastating insect pest of coffee
worldwide with its infestations decreasing crop yield by up to 80%. Caffeine is an alkaloid …

[HTML][HTML] The core metabolome and root exudation dynamics of three phylogenetically distinct plant species

…, K Zhalnina, S Kosina, TR Northen… - Nature …, 2023 - nature.com
Root exudates are plant-derived, exported metabolites likely shaping root-associated
microbiomes by acting as nutrients and signals. However, root exudation dynamics are unclear …

Dealing with the unknown: metabolomics and metabolite atlases

BP Bowen, TR Northen - Journal of the American Society for Mass …, 2010 - Springer
Metabolomics is the comprehensive profiling of the small molecule composition of a
biological sample. Since metabolites are often the indirect products of gene expression, this …

Widespread adenine N6-methylation of active genes in fungi

…, A Clum, E Lindquist, C Daum, TR Northen… - Nature …, 2017 - nature.com
N6-methyldeoxyadenine (6mA) is a noncanonical DNA base modification present at low levels
in plant and animal genomes 1 , 2 , 3 , 4 , but its prevalence and association with genome …