Facioscapulohumeral dystrophy (FSHD) is an autosomal dominant muscular dystrophy in
which no mutation of pathogenic gene(s) has been identified. Instead, the disease is, in most …

Aplastic anaemia in adults is usually acquired, but rarely constitutional types of bone marrow
failure can occur late in life. We assessed two families with onset of pancytopenia in adults …

Background Aplastic anaemia is a bone-marrow-failure syndrome characterised by low
blood-cell counts and fatty bone marrow. In most cases, no obvious aetiological factor can be …

A critical step in protein biomarker discovery is the ability to contrast proteomes, a process
referred generally as quantitative proteomics. While stable-isotope labeling (eg, ICAT, 18 O- …

As the largest energy consumer and CO 2 emitting country, the Chinese government is
committing to a low-carbon economy. It is meaningful and contributes to evaluate and analyze …

With a rapid economic growth and social development in China, the associated problems of
water pollution and shortage of water resources would limit the sustainable and coordinated …

With the rapid economic growth and social development in China, conflicts over water resources
between human and nature are continuously increasing which is attracting the attention …

Heterochromatin Protein 1 (HP1) is a transcriptional repressor that directly binds to the
methylated lysine 9 residue of histone H3 (H3K9me), which is a hallmark histone modification for …

Aneuploidy, especially monosomy 7 and trisomy 8, is a frequent cytogenetic abnormality in
the myelodysplastic syndromes (MDSs). Patients with monosomy 7 and trisomy 8 have …

Early cancer detection by cell-free DNA faces multiple challenges: low fraction of tumor cell-free
DNA, molecular heterogeneity of cancer, and sample sizes that are not sufficient to …