Empiric probiotics are commonly consumed by healthy individuals as means of life quality
improvement and disease prevention. However, evidence of probiotic gut mucosal …

Non-caloric artificial sweeteners (NAS) are among the most widely used food additives
worldwide, regularly consumed by lean and obese individuals alike. NAS consumption is …

Elevated postprandial blood glucose levels constitute a global epidemic and a major risk
factor for prediabetes and type II diabetes, but existing dietary methods for controlling them …

BACKGROUND/AIMS: Weight loss is considered therapeutic for patients with NAFLD.
However, there is no epidemiological evidence that dietary habits are associated with NAFLD. …

Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly
understood, risk for mucosal infection and systemic inflammation. Here, we show in mouse …

Human gut microbiome composition is shaped by multiple factors but the relative contribution
of host genetics remains elusive. Here we examine genotype and microbiome data from …

All domains of life feature diverse molecular clock machineries that synchronize physiological
processes to diurnal environmental fluctuations. However, no mechanisms are known to …

Probiotics are widely prescribed for prevention of antibiotics-associated dysbiosis and
related adverse effects. However, probiotic impact on post-antibiotic reconstitution of the gut …

Host-microbiome co-evolution drives homeostasis and disease susceptibility, yet regulatory
principles governing the integrated intestinal host-commensal microenvironment remain …

Ly6C hi monocytes seed the healthy intestinal lamina propria to give rise to resident CX 3
CR1 + macrophages that contribute to the maintenance of gut homeostasis. Here we report on …