When eukaryotic cells encounter double-stranded RNA, genes of matching sequence are
silenced through RNA interference. Surprisingly, in some animals and plants, the same gene …

Review on the ability of different TLR agonists to orchestrate antitumor immune responses,
or promote tumor growth, underscoring the impact of choosing among TLR agonists when …

Muscle loss during aging and disuse is a highly prevalent and disabling condition, but
knowledge about cellular pathways mediating muscle atrophy is still limited. Given the postmitotic …

Measurements of gaseous SO 2 , NH 3 , and O 3 using IVL passive sampler technology were
obtained during a pilot measurement program initiated as a key component of the newly …

An animal that can transfer gene-regulatory information from somatic cells to germ cells may
be able to communicate changes in the soma from one generation to the next. In the worm …

Double-stranded RNA (dsRNA) triggers RNA interference (RNAi) to silence genes of matching
sequence. In some animals this experimentally induced silencing is transported between …

RNA silencing in Caenorhabditis elegans is transmitted between cells by the transport of
double-stranded RNA (dsRNA). The efficiency of such transmission, however, depends on both …

Age‐related loss of muscle mass and strength (sarcopenia) leads to a decline in physical
function and frailty in the elderly. Among the many proposed underlying causes of sarcopenia, …

The primate TRIM5α proteins have recently been defined as cellular restriction factors,
preventing primate infection by retroviruses from different species. For instance, rhesus TRIM5α (…

The concept of ‘successful aging’ has long intrigued the scientific community. Despite this
long-standing interest, a consensus definition has proven to be a difficult task, due to the …