Rabies is one of the most deadly infectious diseases, with a case-fatality rate approaching
100%. The disease is established on all continents apart from Antarctica; most cases are …

Bats are sources of high viral diversity and high-profile zoonotic viruses worldwide. Although
apparently not pathogenic in their reservoir hosts, some viruses from bats severely affect …

Ticks and the pathogens they transmit constitute a growing burden for human and animal
health worldwide. Vector competence is a component of vectorial capacity and depends on …

Microbiologic infections acquired from animals, known as zoonoses, pose a risk to public
health. An estimated 60% of emerging human pathogens are zoonotic. Of these pathogens,> …

Interleukin-10 (IL-10) is a critical cytokine used by immune cells to suppress inflammation.
Paradoxically, immune cell–derived IL-10 can drive insulin resistance in obesity by …

In March 2020, following the annual International Committee on Taxonomy of Viruses (ICTV)
ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and …

In February 2019, following the annual taxon ratification vote, the order Mononegavirales
was amended by the addition of four new subfamilies and 12 new genera and the creation of …

Dengue viruses (DENV) cause countless human deaths each year, whilst West Nile virus (WNV)
has re-emerged as an important human pathogen. There are currently no WNV or …

West Nile virus (WNV) is transmitted by mosquitoes and causes fever and encephalitis in
humans, equines, and occasionally wild birds. The virus was first isolated in sub-Saharan …

Ebolaviruses (EBOV) (family Filoviridae) cause viral hemorrhagic fevers in humans and non-human
primates when they spill over from their wildlife reservoir hosts with case fatality …