[PDF][PDF] Mitochondrial protein interaction mapping identifies regulators of respiratory chain function

…, A Ulbrich, JA Stefely, SL Bohl, KM Werner, A Jochem… - Molecular cell, 2016 - cell.com
Mitochondria are essential for numerous cellular processes, yet hundreds of their proteins
lack robust functional annotation. To reveal functions for these proteins (termed MXPs), we …

Area-wide roof plane segmentation in airborne LiDAR point clouds

A Jochem, B Höfle, V Wichmann, M Rutzinger… - … , Environment and Urban …, 2012 - Elsevier
Most algorithms performing segmentation of 3D point cloud data acquired by, eg Airborne
Laser Scanning (ALS) systems are not suitable for large study areas because the huge …

Posture, muscle activity and muscle fatigue in prolonged VDT work at different screen height settings

J Seghers, A Jochem, A Spaepen - Ergonomics, 2003 - Taylor & Francis
With the increasing use of video display terminals (VDTs), there is growing concern over the
corresponding increase in the number of health problems reported. Although much …

[HTML][HTML] Automatic roof plane detection and analysis in airborne lidar point clouds for solar potential assessment

A Jochem, B Höfle, M Rutzinger, N Pfeifer - Sensors, 2009 - mdpi.com
A relative height threshold is defined to separate potential roof points from the point cloud,
followed by a segmentation of these points into homogeneous areas fulfilling the defined …

[PDF][PDF] Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthesis

…, A Ulbrich, K Oruganty, BJ Floyd, A Jochem… - Molecular cell, 2015 - cell.com
The ancient UbiB protein kinase-like family is involved in isoprenoid lipid biosynthesis and
is implicated in human diseases, but demonstration of UbiB kinase activity has remained …

Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling

…, EC Freiberger, AL Richards, A Jochem… - Nature …, 2016 - nature.com
Mitochondrial dysfunction is associated with many human diseases, including cancer and
neurodegeneration, that are often linked to proteins and pathways that are not well-…

[PDF][PDF] Cerebellar ataxia and coenzyme Q deficiency through loss of unorthodox kinase activity

…, X Guo, EC Freiberger, L Reutenauer, A Jochem… - Molecular cell, 2016 - cell.com
The UbiB protein kinase-like (PKL) family is widespread, comprising one-quarter of microbial
PKLs and five human homologs, yet its biochemical activities remain obscure. COQ8A (…

Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart Disease Registry (the REMEDY …

…, B Cupido, K Mauff, S Islam, A Joachim… - European heart …, 2015 - academic.oup.com
Aims Rheumatic heart disease (RHD) accounts for over a million premature deaths annually;
however, there is little contemporary information on presentation, complications, and …

[PDF][PDF] Multi-omics reveal specific targets of the RNA-binding protein Puf3p and its orchestration of mitochondrial biogenesis

CP Lapointe, JA Stefely, A Jochem, PD Hutchins… - Cell systems, 2018 - cell.com
Coenzyme Q (CoQ) is a redox-active lipid required for mitochondrial oxidative phosphorylation
(OxPhos). How CoQ biosynthesis is coordinated with the biogenesis of OxPhos protein …

[PDF][PDF] A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis

…, SL Hubler, NM Niemi, DJ Bailey, A Jochem… - Cell metabolism, 2012 - cell.com
Mitochondria are dynamic organelles that play a central role in a diverse array of metabolic
processes. Elucidating mitochondrial adaptations to changing metabolic demands and the …