User profiles for A. Mugler
Andrew MuglerAssociate Professor, Department of Physics and Astronomy, University of Pittsburgh Verified email at pitt.edu Cited by 1983 |
[HTML][HTML] Fundamental limits to cellular sensing
…, NB Becker, TE Ouldridge, A Mugler - Journal of Statistical …, 2016 - Springer
In recent years experiments have demonstrated that living cells can measure low chemical
concentrations with high precision, and much progress has been made in understanding …
concentrations with high precision, and much progress has been made in understanding …
On the convergence of generalized polynomial chaos expansions
OG Ernst, A Mugler, HJ Starkloff… - … Modelling and Numerical …, 2012 - esaim-m2an.org
A number of approaches for discretizing partial differential equations with random data are
based on generalized polynomial chaos expansions of random variables. These constitute …
based on generalized polynomial chaos expansions of random variables. These constitute …
High-speed DNA-based rolling motors powered by RNase H
DNA-based machines that walk by converting chemical energy into controlled motion could
be of use in applications such as next-generation sensors, drug-delivery platforms and …
be of use in applications such as next-generation sensors, drug-delivery platforms and …
Cell–cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis
Collective cell responses to exogenous cues depend on cell–cell interactions. In principle,
these can result in enhanced sensitivity to weak and noisy stimuli. However, this has not yet …
these can result in enhanced sensitivity to weak and noisy stimuli. However, this has not yet …
Analytic methods for modeling stochastic regulatory networks
Recent single-cell experiments have revived interest in the unavoidable or intrinsic noise in
biochemical and genetic networks arising from the small number of molecules of the …
biochemical and genetic networks arising from the small number of molecules of the …
[PDF][PDF] Membrane clustering and the role of rebinding in biochemical signaling
A Mugler, AG Bailey, K Takahashi, PR Ten Wolde - Biophysical journal, 2012 - cell.com
In many cellular signaling pathways, key components form clusters at the cell membrane.
Although much work has focused on the mechanisms behind such cluster formation, the …
Although much work has focused on the mechanisms behind such cluster formation, the …
Limits to the precision of gradient sensing with spatial communication and temporal integration
A Mugler, A Levchenko… - Proceedings of the …, 2016 - National Acad Sciences
Gradient sensing requires at least two measurements at different points in space. These
measurements must then be communicated to a common location to be compared, which is …
measurements must then be communicated to a common location to be compared, which is …
Spectral solutions to stochastic models of gene expression with bursts and regulation
Signal-processing molecules inside cells are often present at low copy number, which
necessitates probabilistic models to account for intrinsic noise. Probability distributions have …
necessitates probabilistic models to account for intrinsic noise. Probability distributions have …
An experimental study of micron-scale droplet aerosols produced via ultrasonic atomization
TD Donnelly, J Hogan, A Mugler, N Schommer… - Physics of …, 2004 - pubs.aip.org
In the last 10 years, laser-driven fusion experiments performed on atomic clusters of deuterium
have shown a surprisingly high neutron yield per joule of input laser energy. Results …
have shown a surprisingly high neutron yield per joule of input laser energy. Results …
Using ultrasonic atomization to produce an aerosol of micron-scale particles
TD Donnelly, J Hogan, A Mugler… - Review of scientific …, 2005 - pubs.aip.org
A device that uses ultrasonic atomization of a liquid to produce an aerosol of micron-scale
droplets is described. This device represents a new approach to producing targets relevant to …
droplets is described. This device represents a new approach to producing targets relevant to …