User profiles for A. Narendran
Aru NarendranAlberta Children's Hospital and The University of Calgary Verified email at ucalgary.ca Cited by 9625 |
[HTML][HTML] Evaluation of COVID-19 vaccine response in patients with cancer: An interim analysis
S Tran, TH Truong, A Narendran - European journal of cancer, 2021 - Elsevier
Background Efficacy and safety data of COVID-19 vaccines among cancer populations have
been limited; however, preliminary data from recent studies have emerged regarding their …
been limited; however, preliminary data from recent studies have emerged regarding their …
Tumour exosome integrins determine organotropic metastasis
…, VD Dumont-Cole, K Kramer, LH Wexler, A Narendran… - Nature, 2015 - nature.com
Ever since Stephen Paget’s 1889 hypothesis, metastatic organotropism has remained one
of cancer’s greatest mysteries. Here we demonstrate that exosomes from mouse and human …
of cancer’s greatest mysteries. Here we demonstrate that exosomes from mouse and human …
Profound block in thymocyte development in mice lacking p56lck
…, DP Siderovskid, W Van Ewijk, A Narendran… - Nature, 1992 - nature.com
THE protein Lck (p56 lck ) has a relative molecular mass of 56,000 and belongs to the Src
family of tyrosine kinases 1–3 . It is expressed exclusively in lymphoid cells, predominantly in …
family of tyrosine kinases 1–3 . It is expressed exclusively in lymphoid cells, predominantly in …
[HTML][HTML] Chemical and conformational diversity of modified nucleosides affects tRNA structure and function
VYP Väre, ER Eruysal, A Narendran, KL Sarachan… - Biomolecules, 2017 - mdpi.com
RNAs are central to all gene expression through the control of protein synthesis. Four major
nucleosides, adenosine, guanosine, cytidine and uridine, compose RNAs and provide …
nucleosides, adenosine, guanosine, cytidine and uridine, compose RNAs and provide …
Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4
…, TM Kündig, SR Sambhara, A Narendran… - Nature, 1991 - nature.com
T CELLS express T-cell antigen receptors (TCR) for the recognition of antigen in conjunction
with the products of the major histocompatibility complex 1,2 . They also express two key …
with the products of the major histocompatibility complex 1,2 . They also express two key …
[HTML][HTML] Survivin as a preferential target for cancer therapy
M Mobahat, A Narendran, K Riabowol - International journal of molecular …, 2014 - mdpi.com
Cancer is typically a consequence of imbalance between cell death and proliferation in a way
favorable to cell proliferation and survival. Most conventional cancer therapies are based …
favorable to cell proliferation and survival. Most conventional cancer therapies are based …
Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development
…, A Wakeham, J Potter, CL Furlonger, A Narendran… - Cell, 1993 - cell.com
Interferon regulatory factor 1 (IRF-1), a transcriptional activator, and its antagonistic repressor,
IRF-2, were originally identified as regulators of the type I interferon (IFN) system. We have …
IRF-2, were originally identified as regulators of the type I interferon (IFN) system. We have …
Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional …
PM Miettunen, A Narendran, A Jayanthan… - …, 2011 - academic.oup.com
SIR, Macrophage activation syndrome (MAS) belongs to the haemophagocytic lymphohistiocytic
(HLH) disorders, and is one of the most feared complications of paediatric inflammatory …
(HLH) disorders, and is one of the most feared complications of paediatric inflammatory …
Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing
…, KA Everette, A Azzun, H Gelfer, CS Seet, A Narendran… - Cell, 2023 - cell.com
CD3δ SCID is a devastating inborn error of immunity caused by mutations in CD3D, encoding
the invariant CD3δ chain of the CD3/TCR complex necessary for normal thymopoiesis. …
the invariant CD3δ chain of the CD3/TCR complex necessary for normal thymopoiesis. …
[HTML][HTML] GM-CSF increases mucosal and systemic immunogenicity of an H1N1 influenza DNA vaccine administered into the epidermis of non-human primates
PT Loudon, EJ Yager, DT Lynch, A Narendran… - PloS one, 2010 - journals.plos.org
Background The recent H5N1 avian and H1N1 swine-origin influenza virus outbreaks
reaffirm that the threat of a world-wide influenza pandemic is both real and ever-present. …
reaffirm that the threat of a world-wide influenza pandemic is both real and ever-present. …