User profiles for B. A. Williams

Brent Williams

Allegheny Health Network
Verified email at ahn.org
Cited by 7422

Mapping and quantifying mammalian transcriptomes by RNA-Seq

A Mortazavi, BA Williams, K McCue, L Schaeffer… - Nature …, 2008 - nature.com
We have mapped and quantified mouse transcriptomes by deeply sequencing them and
recording how frequently each gene is represented in the sequence sample (RNA-Seq). This …

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

C Trapnell, BA Williams, G Pertea, A Mortazavi… - Nature …, 2010 - nature.com
High-throughput mRNA sequencing (RNA-Seq) promises simultaneous transcript discovery
and abundance estimation 1 , 2 , 3 . However, this would require algorithms that are not …

[HTML][HTML] Landscape of transcription in human cells

…, C Xue, GK Marinov, J Khatun, BA Williams… - Nature, 2012 - nature.com
Eukaryotic cells make many types of primary and processed RNAs that are found either in
specific subcellular compartments or throughout the cells. A complete catalogue of these …

A simple gas production method using a pressure transducer to determine the fermentation kinetics of ruminant feeds

MK Theodorou, BA Williams, MS Dhanoa… - Animal feed science and …, 1994 - Elsevier
This paper describes a simple yet sensitive laboratory procedure that was developed to
provide detailed information on the fermentation kinetics of ruminant feeds. In principle, the …

[HTML][HTML] Expanded encyclopaedias of DNA elements in the human and mouse genomes

…, Y He, M Mackiewicz, F Pauli-Behn, BA Williams… - Nature, 2020 - nature.com
The human and mouse genomes contain instructions that specify RNAs and proteins and
govern the timing, magnitude, and cellular context of their production. To better delineate these …

[HTML][HTML] A comparative encyclopedia of DNA elements in the mouse genome

…, E Rynes, A Kirilusha, GK Marinov, BA Williams… - Nature, 2014 - nature.com
The laboratory mouse shares the majority of its protein-coding genes with humans, making
it the premier model organism in biomedical research, yet the two mammals differ in …

Psychiatric disorders and repeat incarcerations: the revolving prison door

…, IA Binswanger, JV Penn, BA Williams… - American Journal of …, 2009 - Am Psychiatric Assoc
Objective: A number of legal, social, and political factors over the past 40 years have led to
the current epidemic of psychiatric disorders in the US prison system. Although numerous …

Acute myocardial infarction and renal dysfunction: a high-risk combination

…, CA Herzog, RC Albright, BA Williams… - Annals of internal …, 2002 - acpjournals.org
Background: Survival is poor in patients with acute myocardial infarction (MI) who also have
severe renal disease. Less is known about the outcome of acute MI in patients with mild to …

Dynamic DNA methylation across diverse human cell lines and tissues

…, F Pauli-Behn, MK Cross, BA Williams… - Genome …, 2013 - genome.cshlp.org
As studies of DNA methylation increase in scope, it has become evident that methylation has
a complex relationship with gene expression, plays an important role in defining cell types, …

Multiphasic analysis of gas production kinetics for in vitro fermentation of ruminant feeds

JCJ Groot, JW Cone, BA Williams… - Animal Feed Science …, 1996 - Elsevier
Recently developed time-related gas production techniques to quantify the kinetics of
ruminant feed fermentation have a high resolution. Consequently, fermentation processes with …