High-throughput mRNA sequencing (RNA-Seq) promises simultaneous transcript discovery
and abundance estimation 1 , 2 , 3 . However, this would require algorithms that are not …

Chromatin immunoprecipitation (ChIP) followed by high-throughput DNA sequencing (ChIP-seq)
has become a valuable and widely used approach for mapping the genomic location of …

Repair and regeneration of adult skeletal muscle are mediated by satellite cells. In healthy
muscle these rare mononucleate muscle precursor cells are mitotically quiescent. Upon …

As studies of DNA methylation increase in scope, it has become evident that methylation has
a complex relationship with gene expression, plays an important role in defining cell types, …

The most widely used strategy for gene disruption in the mouse involves the deletion of part
or all of the target gene together with concomitant insertion of a drug selection cassette, the …

… We thank Henry Amrhein, Diane Trout, and Sean Upchurch for computational assistance,
and members of the Wold laboratory for helpful discussions. This work has been supported by …

… a Recent reevaluation established that the primer set identified above as c-met-A that was
used previously (Cornelison and Wold, 1997) and in this work does not cross an intron border …

High-throughput mRNA sequencing (RNA-Seq) holds the promise of simultaneous
transcript discovery and abundance estimation 1-3. We introduce an algorithm for transcript …

To complement the human Encyclopedia of DNA Elements (ENCODE) project and to enable
a broad range of mouse genomics efforts, the Mouse ENCODE Consortium is applying the …

T cell development comprises a stepwise process of commitment from a multipotent precursor.
To define molecular mechanisms controlling this progression, we probed five stages …