Coffee, a major dietary source of caffeine, is among the most widely consumed beverages in
the world and has received considerable attention regarding health risks and benefits. We …

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta-…

Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide
significance that together explained one-fifth of the heritability for adult height. By testing …

In recent years, a number of different technologies have been proposed for use in reflective
displays 1 , 2 , 3 . One of the most appealing applications of a reflective display is electronic …

… The intercept of this regression (b 0 ) appears to be due to cryptic relatedness because
when we eliminated relatives with a relationship >0.025, b 0 declined to zero (Fig. 3). We …

We detected clonal mosaicism for large chromosomal anomalies (duplications, deletions
and uniparental disomy) using SNP microarray data from over 50,000 subjects recruited for …

Age at menarche is a marker of timing of puberty in females. It varies widely between
individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, …

To identify loci for age at menarche, we performed a meta-analysis of 32 genome-wide
association studies in 87,802 women of European descent, with replication in up to 14,731 …

… PPP2R3C (a protein phosphatase component regulating B cell maturation and survival),
the … functions, including roles in T H 17 and B cell differentiation and function; ETS1-deficient …

Although physical activity and sedentary behavior are moderately heritable, little is known
about the mechanisms that influence these traits. Combining data for up to 703,901 …