Background During the past 25 years, many pregnancy and birth cohorts have been
established. Each cohort provides unique opportunities for examining associations of early‐life …

… Deficiency in group B vitamins has been associated with neural tube defects, delayed
language development and impaired motor functioning [209]. Micronutrients including iron, …

Type 2 diabetes mellitus results from the interaction of environmental factors with a combination
of genetic variants, most of which were hitherto unknown. A systematic search for these …

… Risk of biasb … b From 0 to 5, a higher score indicating a higher risk of bias. … (b) Paper
distribution according to the total risk of bias (sum of the five quality criteria). …

Epigenetic modifications, including DNA methylation, represent a potential mechanism for
environmental impacts on human disease. Maternal smoking in pregnancy remains an …

We analyzed genome-wide association data from 1,380 Europeans with early-onset and
morbid adult obesity and 1,416 age-matched normal-weight controls. Thirty-eight markers …

In genome-wide association (GWA) data from 2,151 nondiabetic French subjects, we
identified rs1387153, near MTNR1B (which encodes the melatonin receptor 2 (MT2)), as a …

Background Ambient air pollution has been associated with restricted fetal growth, which is
linked with adverse respiratory health in childhood. We assessed the effect of maternal …

Objective To assess the separate and combined associations of maternal pre‐pregnancy
body mass index (BMI) and gestational weight gain with the risks of pregnancy complications …

Barker’s hypothesis suggests that health in adulthood can be influenced by events occurring
during the developmental period. 1 Studies from various parts of the world have shown …