Horizontal gene transfer is an important mechanism of microbial evolution and is often driven
by the movement of mobile genetic elements between cells. Due to the fact that microbes …

Although metals are essential for the molecular machineries of life, systematic methods for
discovering metal–small molecule complexes from biological samples are limited. Here, we …

Background: Machine learning and artificial intelligence have shown promising results in
many areas and are driven by the increasing amount of available data. However, these data …

To fully leverage big data, they need to be shared across institutions in a manner compliant
with privacy considerations and the EU General Data Protection Regulation (GDPR) …

Proteus mirabilis is a social bacterium that is capable of self (kin) versus nonself recognition.
Swarming colonies of this bacterium expand outward on surfaces to centimeter-scale …

Microbiomes are intricately intertwined with human health, geochemical cycles, and food
production. While many microbiomes of interest are highly complex and experimentally …

The bacterium Proteus mirabilis can communicate identity through the secretion of the self-identity
protein IdsD via the type VI secretion (T6S) system. IdsD secretion is essential for self-…

The type VI secretion (T6S) system is a molecular device for the delivery of proteins from
one cell into another. T6S function depends on the contractile sheath comprised of TssB/VipA …

Metals are essential for the molecular machineries of life, and microbes have evolved a variety
of small molecules to acquire, compete for, and utilize metals. Systematic methods for the …

… Chapter 3 The self-identity protein IdsD is communicated between cells in swarming Proteus
mirabilis colonies Most of the work presented in this chapter was published as Saak CC, …