Cohesin: its roles and mechanisms
K Nasmyth, CH Haering - Annual review of genetics, 2009 - annualreviews.org
… C terminus of Smc3 but not by fusing its C terminus to the N terminus of Smc1 (43). The
dependency of the interaction on prior binding of the Scc1's C … residues within Scc1's C-terminal …
dependency of the interaction on prior binding of the Scc1's C … residues within Scc1's C-terminal …
The structure and function of SMC and kleisin complexes
K Nasmyth, CH Haering - Annu. Rev. Biochem., 2005 - annualreviews.org
… Crucially, an antibody specific to XCAP-C blocked formation of mitotic chromatids in egg …
Antibodies specific to XCAP-C and -E were subsequently used to affinity purify XCAP-C/E …
Antibodies specific to XCAP-C and -E were subsequently used to affinity purify XCAP-C/E …
[PDF][PDF] Towards a unified model of SMC complex function
M Hassler, IA Shaltiel, CH Haering - Current Biology, 2018 - cell.com
… Asymmetric loop extrusion is expected to produce ‘stripes’ in Hi-C contact maps and might
… and members of the Haering lab for many stimulating discussions. Work in the Haering lab is …
… and members of the Haering lab for many stimulating discussions. Work in the Haering lab is …
Two independent modes of chromatin organization revealed by cohesin removal
… us to pool the two replicate data sets to generate Hi-C maps for the three different conditions.
We compared Hi-C maps for ΔNipbl and control cells by examining compartments, TADs, …
We compared Hi-C maps for ΔNipbl and control cells by examining compartments, TADs, …
[PDF][PDF] Molecular architecture of SMC proteins and the yeast cohesin complex
CH Haering, J Löwe, A Hochwagen, K Nasmyth - Molecular cell, 2002 - cell.com
… SMC proteins share a five-domain structure, with a large proteinaceous loop within which
sister chroglobular N- and C-terminal domains separated by a long matids might be entrapped …
sister chroglobular N- and C-terminal domains separated by a long matids might be entrapped …
[HTML][HTML] Chromosomal cohesin forms a ring
S Gruber, CH Haering, K Nasmyth - Cell, 2003 - cell.com
… We show that N- and C-terminal Scc1 cleavage fragments remain connected due to their
association with different heads of a single Smc1/Smc3 heterodimer. Cleavage of the Smc3 …
association with different heads of a single Smc1/Smc3 heterodimer. Cleavage of the Smc3 …
Real-time imaging of DNA loop extrusion by condensin
It has been hypothesized that SMC protein complexes such as condensin and cohesin
spatially organize chromosomes by extruding DNA into large loops. We directly visualized the …
spatially organize chromosomes by extruding DNA into large loops. We directly visualized the …
The cohesin ring concatenates sister DNA molecules
CH Haering, AM Farcas, P Arumugam, J Metson… - Nature, 2008 - nature.com
… a, Fusion of the C terminus of Smc3 with the N terminus of … c, The structure of the yeast Scc1
C terminus bound to the … yeast Smc1 head domain bound to the C-terminal domain of Scc1 …
C terminus bound to the … yeast Smc1 head domain bound to the C-terminal domain of Scc1 …
Degradation of the electrical conductivity in stabilised zirconia system: Part II: Scandia-stabilised zirconia
C Haering, A Roosen, H Schichl, M Schnöller - Solid State Ionics, 2005 - Elsevier
Scandia-stabilised zirconia (ScSZ) electrolyte materials exhibit the highest conductivity of all
the zirconia systems, but the degradation in the ScSZ system has only been investigated yet …
the zirconia systems, but the degradation in the ScSZ system has only been investigated yet …
[PDF][PDF] Structure and stability of cohesin's Smc1-kleisin interaction
CH Haering, D Schoffnegger, T Nishino, W Helmhart… - Molecular cell, 2004 - cell.com
… crystal structure of Smc1's ATPase complexed with Scc1's C-terminal domain. The latter forms
a … Interaction of Scc1's N terminus with Smc3 depends on prior C terminus connection with …
a … Interaction of Scc1's N terminus with Smc3 depends on prior C terminus connection with …