User profiles for D. A. Vargas

Diego A Vargas

Postdoctoral fellow
Verified email at dewpointx.com
Cited by 180

[HTML][HTML] Time-of-day effects on short-duration maximal exercise performance

GG Mirizio, RSM Nunes, DA Vargas, C Foster… - Scientific reports, 2020 - nature.com
Time-of-day dependent fluctuations in exercise performance have been documented across
different sports and seem to affect both endurance and resistance modes of exercise. Most …

Myoglobin‐Catalyzed C− H Functionalization of Unprotected Indoles

DA Vargas, A Tinoco, V Tyagi… - Angewandte Chemie …, 2018 - Wiley Online Library
Functionalized indoles are recurrent motifs in bioactive natural products and pharmaceuticals.
While transition metal‐catalyzed carbene transfer has provided an attractive route to …

[HTML][HTML] Incidence and risk factor prevalence of community-acquired pneumonia in adults in primary care in Spain (NEUMO-ES-RISK project)

I Rivero-Calle, J Pardo-Seco, P Aldaz, DA Vargas… - BMC infectious …, 2016 - Springer
Background Community-acquired pneumonia (CAP) is a major cause of morbidity and
mortality in adults even in developed countries. Several lifestyle factors and comorbidities have …

Referral Criteria for Asthma: Consensus Document.

T Gómez, ÁG FJ, VO DA, ÁP MJ, CG JA - Journal of investigational …, 2019 - europepmc.org
Asthma is one of the most prevalent chronic diseases in Spain. Current treatments ensure
that the disease is controlled in most cases. However, disease is often uncontrolled in daily …

Mdm2: A regulator of cell growth and death

DA Vargas, S Takahashi, Z Ronai - Advances in cancer research, 2003 - books.google.com
The interplay between Mdm2 and p53 represents one of the better-known paradigms of the
relationship between an oncogene and a tumor suppressor gene. The Mdm2 protein is a key …

Biocatalytic strategy for highly diastereo‐and enantioselective synthesis of 2, 3‐dihydrobenzofuran‐based tricyclic scaffolds

DA Vargas, RL Khade, Y Zhang… - Angewandte Chemie …, 2019 - Wiley Online Library
2,3‐Dihydrobenzofurans are key pharmacophores in many natural and synthetic bioactive
molecules. A biocatalytic strategy is reported here for the highly diastereo‐ and …

Engineering of RuMb: Toward a green catalyst for carbene insertion reactions

MW Wolf, DA Vargas, N Lehnert - Inorganic Chemistry, 2017 - ACS Publications
The small, stable heme protein myoglobin (Mb) was modified through cofactor substitution
and mutagenesis to develop a new catalyst for carbene transfer reactions. The native heme …

[HTML][HTML] Bio-mapping indicators and pathogen loads in a commercial broiler processing facility operating with high and low antimicrobial intervention levels

JF De Villena, DA Vargas, R Bueno López… - Foods, 2022 - mdpi.com
The poultry industry in the United States has traditionally implemented non-chemical and
chemical interventions against Salmonella spp. and Campylobacter spp. on the basis of …

[PDF][PDF] Darwin's finches combat introduced nest parasites with fumigated cotton

SA Knutie, SM McNew, AW Bartlow, DA Vargas… - Current Biology, 2014 - cell.com
Introduced parasites are a threat to biodiversity when naïve hosts lack effective defenses
against such parasites [1]. Several parasites have recently colonized the Galápagos Islands, …

[HTML][HTML] The role of actin protrusion dynamics in cell migration through a degradable viscoelastic extracellular matrix: Insights from a computational model

T Heck, DA Vargas, B Smeets, H Ramon… - PLoS computational …, 2020 - journals.plos.org
Actin protrusion dynamics plays an important role in the regulation of three-dimensional (3D)
cell migration. Cells form protrusions that adhere to the surrounding extracellular matrix (…