User profiles for D. K. Merriman

Dawn Kellogg Merriman

Ph.D.
Verified email at afit.edu
Cited by 535

Diurnal rodents as pertinent animal models of human retinal physiology and pathology

DM Verra, BS Sajdak, DK Merriman, D Hicks - Progress in Retinal and Eye …, 2020 - Elsevier
This presentation will survey the retinal architecture, advantages, and limitations of several
lesser-known rodent species that provide a useful diurnal complement to rats and mice. …

Inhibition of Borna disease virus replication by an endogenous bornavirus-like element in the ground squirrel genome

…, M Horie, T Honda, DK Merriman… - Proceedings of the …, 2014 - National Acad Sciences
Animal genomes contain endogenous viral sequences, such as endogenous retroviruses and
retrotransposons. Recently, we and others discovered that nonretroviral viruses also have …

[PDF][PDF] iPSCs from a hibernator provide a platform for studying cold adaptation and its potential medical applications

…, KJ Miyagishima, Y Xu, H Zhou, J Chen, DK Merriman… - Cell, 2018 - cell.com
Hibernating mammals survive hypothermia (<10C) without injury, a remarkable feat of
cellular preservation that bears significance for potential medical applications. However, …

Low-cost functional plasticity of TRPV1 supports heat tolerance in squirrels and camels

…, ER Schneider, DK Merriman… - Proceedings of the …, 2016 - National Acad Sciences
The ability to sense heat is crucial for survival. Increased heat tolerance may prove
beneficial by conferring the ability to inhabit otherwise prohibitive ecological niches. This …

[PDF][PDF] Molecular prerequisites for diminished cold sensitivity in ground squirrels and hamsters

…, ER Schneider, M Mastrotto, DK Merriman… - Cell reports, 2017 - cell.com
Thirteen-lined ground squirrels and Syrian hamsters are known for their ability to withstand
cold during hibernation. We found that hibernators exhibit cold tolerance even in the active …

High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble

…, J Lee, A Rangadurai, DK Merriman… - Nature structural & …, 2018 - nature.com
Dynamic ensembles hold great promise in advancing RNA-targeted drug discovery. Here we
subjected the transactivation response element (TAR) RNA from human immunodeficiency …

[HTML][HTML] A potentially abundant junctional RNA motif stabilized by m6A and Mg2+

B Liu, DK Merriman, SH Choi, MA Schumacher… - Nature …, 2018 - nature.com
N 6 -Methyladenosine (m 6 A) is an abundant post-transcriptional RNA modification that
influences multiple aspects of gene expression. In addition to recruiting proteins, m 6 A can …

Insights into Watson–Crick/Hoogsteen breathing dynamics and damage repair from the solution structure and dynamic ensemble of DNA duplexes containing m1A

…, Y Xue, A Rangadurai, DK Merriman… - Nucleic acids …, 2017 - academic.oup.com
In the canonical DNA double helix, Watson–Crick (WC) base pairs (bps) exist in dynamic
equilibrium with sparsely populated (∼0.02–0.4%) and short-lived (lifetimes ∼0.2–2.5 ms) …

[HTML][HTML] Differential composition of DHA and very-long-chain PUFAs in rod and cone photoreceptors

MP Agbaga, DK Merriman, RS Brush, TA Lydic… - Journal of lipid …, 2018 - ASBMB
Long-chain PUFAs (LC-PUFAs; C20–C22; eg, DHA and arachidonic acid) are highly enriched
in vertebrate retina, where they are elongated to very-long-chain PUFAs (VLC-PUFAs; C …

Seasonal and post-trauma remodeling in cone-dominant ground squirrel retina

DK Merriman, BS Sajdak, W Li, BW Jones - Experimental Eye Research, 2016 - Elsevier
With a photoreceptor mosaic containing ∼85% cones, the ground squirrel is one of the
richest known mammalian sources of these important retinal cells. It also has a visual ecology …