User profiles for D. Cousminer

Diana L Cousminer

GSK
Verified email at gsk.com
Cited by 7456

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

…, KL Lunetta, JA Visser, EM Byrne, DL Cousminer… - Nature …, 2010 - nature.com
To identify loci for age at menarche, we performed a meta-analysis of 32 genome-wide
association studies in 87,802 women of European descent, with replication in up to 14,731 …

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

…, E Albrecht, WQ Ang, T Corre, DL Cousminer… - Nature, 2014 - nature.com
Age at menarche is a marker of timing of puberty in females. It varies widely between
individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, …

A global perspective of latent autoimmune diabetes in adults

R Mishra, KM Hodge, DL Cousminer, RD Leslie… - Trends in Endocrinology …, 2018 - cell.com
Latent autoimmune diabetes in adults (LADA) is characterized by the presence of islet
autoantibodies and initial insulin independence, which can lead to misdiagnosis of type 2 …

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

…, T Corre, FJ Couch, DL Cousminer… - Nature …, 2017 - nature.com
The timing of puberty is a highly polygenic childhood trait that is epidemiologically associated
with various adult diseases. Using 1000 Genomes Project–imputed genotype data in up to …

Genome-wide associations for birth weight and correlations with adult disease

…, E Kreiner, R Rueedi, LP Lyytikäinen, DL Cousminer… - Nature, 2016 - nature.com
Birth weight (BW) has been shown to be influenced by both fetal and maternal factors and in
observational studies is reproducibly associated with future risk of adult metabolic diseases …

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

…, A Cavadino, S Metrustry, DL Cousminer… - Nature …, 2019 - nature.com
Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors,
and has been reproducibly associated with future cardio-metabolic health outcomes. In …

Meta-analysis of genome-wide association studies for personality

…, I Giegling, B Konte, E Widen, DL Cousminer… - Molecular …, 2012 - nature.com
Personality can be thought of as a set of characteristics that influence people's thoughts,
feelings and behavior across a variety of settings. Variation in personality is predictive of many …

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

…, DM Evans, P Charoen, M Kaakinen, DL Cousminer… - Nature …, 2013 - nature.com
Birth weight within the normal range is associated with a variety of adult-onset diseases, but
the mechanisms behind these associations are poorly understood 1 . Previous genome-…

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

…, MM Groen-Blokhuis, DL Cousminer… - Human molecular …, 2016 - academic.oup.com
A large number of genetic loci are associated with adult body mass index. However, the
genetics of childhood body mass index are largely unknown. We performed a meta-analysis of …

[HTML][HTML] New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

…, ML Buchkovich, J Na, V Bataille, DL Cousminer… - Nature …, 2016 - nature.com
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic
disease risk, we conducted a genome-wide association meta-analysis of body fat …