User profiles for D. Cousminer
Diana L CousminerGSK Verified email at gsk.com Cited by 7456 |
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
To identify loci for age at menarche, we performed a meta-analysis of 32 genome-wide
association studies in 87,802 women of European descent, with replication in up to 14,731 …
association studies in 87,802 women of European descent, with replication in up to 14,731 …
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
…, E Albrecht, WQ Ang, T Corre, DL Cousminer… - Nature, 2014 - nature.com
Age at menarche is a marker of timing of puberty in females. It varies widely between
individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, …
individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, …
A global perspective of latent autoimmune diabetes in adults
Latent autoimmune diabetes in adults (LADA) is characterized by the presence of islet
autoantibodies and initial insulin independence, which can lead to misdiagnosis of type 2 …
autoantibodies and initial insulin independence, which can lead to misdiagnosis of type 2 …
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk
…, T Corre, FJ Couch, DL Cousminer… - Nature …, 2017 - nature.com
The timing of puberty is a highly polygenic childhood trait that is epidemiologically associated
with various adult diseases. Using 1000 Genomes Project–imputed genotype data in up to …
with various adult diseases. Using 1000 Genomes Project–imputed genotype data in up to …
Genome-wide associations for birth weight and correlations with adult disease
…, E Kreiner, R Rueedi, LP Lyytikäinen, DL Cousminer… - Nature, 2016 - nature.com
Birth weight (BW) has been shown to be influenced by both fetal and maternal factors and in
observational studies is reproducibly associated with future risk of adult metabolic diseases …
observational studies is reproducibly associated with future risk of adult metabolic diseases …
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
…, A Cavadino, S Metrustry, DL Cousminer… - Nature …, 2019 - nature.com
Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors,
and has been reproducibly associated with future cardio-metabolic health outcomes. In …
and has been reproducibly associated with future cardio-metabolic health outcomes. In …
Meta-analysis of genome-wide association studies for personality
…, I Giegling, B Konte, E Widen, DL Cousminer… - Molecular …, 2012 - nature.com
Personality can be thought of as a set of characteristics that influence people's thoughts,
feelings and behavior across a variety of settings. Variation in personality is predictive of many …
feelings and behavior across a variety of settings. Variation in personality is predictive of many …
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
Birth weight within the normal range is associated with a variety of adult-onset diseases, but
the mechanisms behind these associations are poorly understood 1 . Previous genome-…
the mechanisms behind these associations are poorly understood 1 . Previous genome-…
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
…, MM Groen-Blokhuis, DL Cousminer… - Human molecular …, 2016 - academic.oup.com
A large number of genetic loci are associated with adult body mass index. However, the
genetics of childhood body mass index are largely unknown. We performed a meta-analysis of …
genetics of childhood body mass index are largely unknown. We performed a meta-analysis of …
[HTML][HTML] New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
…, ML Buchkovich, J Na, V Bataille, DL Cousminer… - Nature …, 2016 - nature.com
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic
disease risk, we conducted a genome-wide association meta-analysis of body fat …
disease risk, we conducted a genome-wide association meta-analysis of body fat …