The genomes of virtually all organisms contain repetitive sequences that are generated by
the activity of transposable elements (transposons). Transposons are mobile genetic …

The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium (CPTAC)
investigates tumors from a proteogenomic perspective, creating rich multi-omics datasets …

With combined technological advancements in high-throughput next-generation sequencing
and deep mass spectrometry-based proteomics, proteogenomics, ie the integrative …

Somatic mutations have been extensively characterized in breast cancer, but the effects of
these genetic alterations on the proteomic landscape remain poorly understood. Here we …

Passive transfer of broadly neutralizing HIV antibodies can prevent infection, which suggests
that vaccines that elicit such antibodies would be protective. Thus far, however, few broadly …

To provide a detailed analysis of the molecular components and underlying mechanisms
associated with ovarian cancer, we performed a comprehensive mass-spectrometry-based …

… d, Distribution of the number of tiles per slide. … 10, the values of the last fully connected
layer are visualized using a t-SNE representation, which generates 2-D scatterplots of high-…

To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and …

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient
survival. Toward understanding the underlying molecular alterations that drive PDAC …

We performed the first proteogenomic study on a prospectively collected colon cancer cohort.
Comparative proteomic and phosphoproteomic analysis of paired tumor and normal …