User profiles for D. Reich

Daniel S. Reich

- Verified email at nih.gov - Cited by 24269

David L Reich

- Verified email at mountsinai.org - Cited by 22597

A draft sequence of the Neandertal genome

…, M Slatkin, R Nielsen, J Kelso, M Lachmann, D Reich… - science, 2010 - science.org
Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of
Europe and western Asia before disappearing 30,000 years ago. We present a draft …

Linkage disequilibrium in the human genome

DE Reich, M Cargill, S Bolk, J Ireland, PC Sabeti… - Nature, 2001 - nature.com
D′ has the same range of values regardless of the frequencies of the SNPs compared 11
. … that caused D′ > 0 in Utah so that, in comparisons with other populations, the sign of D′ …

Principal components analysis corrects for stratification in genome-wide association studies

…, RM Plenge, ME Weinblatt, NA Shadick, D Reich - Nature …, 2006 - nature.com
Population stratification—allele frequency differences between cases and controls due to
systematic ancestry differences—can cause spurious associations in disease studies. We …

2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with thoracic aortic disease: a report of the …

…, NT Kouchoukos, BW Lytle, DM Milewicz, DL Reich… - Circulation, 2010 - Am Heart Assoc
… Specifically targeted searches were conducted on the following subtopics: acute aortic
dissection, ankylosing spondylitis, aortic dissection and litigation, aortic neoplasm, aortic tumors …

On the allelic spectrum of human disease

DE Reich, ES Lander - TRENDS in Genetics, 2001 - cell.com
… The locus has disease alleles d 1 , d 2 , d 3 , etc., assumed to be selectively equivalent. Let
f be the total frequency of the set of disease alleles in the current population; that is, the sum …

2021 MAGNIMS–CMSC–NAIMS consensus recommendations on the use of MRI in patients with multiple sclerosis

MP Wattjes, O Ciccarelli, DS Reich, B Banwell… - The Lancet …, 2021 - thelancet.com
The 2015 Magnetic Resonance Imaging in Multiple Sclerosis and 2016 Consortium of Multiple
Sclerosis Centres guidelines on the use of MRI in diagnosis and monitoring of multiple …

[HTML][HTML] An inflammatory cytokine signature predicts COVID-19 severity and survival

…, A Firpo-Betancourt, DR Mendu, J Jhang, D Reich… - Nature medicine, 2020 - nature.com
Several studies have revealed that the hyper-inflammatory response induced by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major cause of disease severity …

[HTML][HTML] Genetic history of an archaic hominin group from Denisova Cave in Siberia

D Reich, RE Green, M Kircher, J Krause, N Patterson… - Nature, 2010 - nature.com
… We used the D statistic 8 to test if various pairs of present-day humans share equal … , the D
statistics are qualitatively unchanged (Supplementary Information section 10). Similarly, the D

Robust neutralizing antibodies to SARS-CoV-2 infection persist for months

…, K Stone, S Strohmeier, V Simon, J Aberg, DL Reich… - Science, 2020 - science.org
… We also thank RA Albrecht for oversight of the conventional Biosafety Level 3 biocontainment
facility, the medical students involved in the plasma convalescence program, and D. …

Detecting recent positive selection in the human genome from haplotype structure

PC Sabeti, DE Reich, JM Higgins, HZP Levine… - Nature, 2002 - nature.com
… c, d, We performed the entire analysis again on G6PD (c) and TNFSF5 (d) for a subset of 78
Yoruban haplotypes (using family trios where phase could be determined). We were able to …