… role for extra-neutralizing, eg Fc-mediated, 2G12 activities under the conditions of the
experiment, and (3) a critical role for 2G12 inhibition of virus interaction with lectin, eg DC-SIGN, …

… Although almost all Env protein immunogens (eg, gp120 monomers, uncleaved gp140s) can
raise NAbs against various neutralization-sensitive tier 1 viruses, the induction of NAbs that …

Most animal studies using passive administration of HIV broadly neutralizing monoclonal
antibodies (bnMAbs) have associated protection against high-dose mucosal viral challenge …

Infection with Asian-lineage Zika virus (ZIKV) has been associated with Guillain–Barré
syndrome and fetal abnormalities, but the underlying mechanisms remain poorly understood. …

The membrane-proximal external region (MPER) of HIV-1, located at the C terminus of the
gp41 ectodomain, is conserved and crucial for viral fusion. Three broadly neutralizing …

CD8+ T cells are a key focus of vaccine development efforts for HIV. However, there is no
clear consensus as to which of the nine HIV proteins should be used for vaccination. The early …

… Vertical boxes, eg, that corresponding to animal 95071 for Nef YY9-159, indicate responses
detected by tetramers but not by IFN-γ secretion. Variation in known epitopes is represented …

Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …

Tetherin is an IFN-inducible transmembrane protein that inhibits the detachment of enveloped
viruses from infected cells. HIV-1 overcomes this restriction factor by expressing HIV-1 …

… It is not known whether the differences between African and Asian lineage ZIKV have any
phenotypic impact, eg, increased transmissibility or pathogenicity. Because human infections …