A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus
There is an urgent need for an effective, oral, direct-acting therapeutic to block transmission
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent progression …
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent progression …
Molnupiravir, an oral antiviral treatment for COVID-19
Background Easily distributed oral antivirals are urgently needed to treat coronavirus
disease-2019 (COVID-19), prevent progression to severe illness, and block transmission of severe …
disease-2019 (COVID-19), prevent progression to severe illness, and block transmission of severe …
Sugar levels modulate differential expression of maize sucrose synthase genes.
KE Koch, KD Nolte, ER Duke, DR McCarty… - The Plant …, 1992 - academic.oup.com
… (ER Duke, DR McCarty, LC Hannah, and KE Koch, unpublished data). The assay involved
recovery of radiolabeled reaction product on DEAE ion exchange paper, an approach initially …
recovery of radiolabeled reaction product on DEAE ion exchange paper, an approach initially …
Effect of molnupiravir on biomarkers, respiratory interventions, and medical services in COVID-19: a randomized, placebo-controlled trial
…, PA Moncada, L Burgess, ER Duke… - Annals of internal …, 2022 - acpjournals.org
Background: In the MOVe-OUT trial, molnupiravir showed a clinically meaningful reduction
in the risk for hospitalization or death in adults with mild to moderate COVID-19 and risk …
in the risk for hospitalization or death in adults with mild to moderate COVID-19 and risk …
[HTML][HTML] A majority of HIV persistence during antiretroviral therapy is due to infected cell proliferation
Antiretroviral therapy (ART) suppresses viral replication in people living with HIV. Yet, infected
cells persist for decades on ART and viremia returns if ART is stopped. Persistence has …
cells persist for decades on ART and viremia returns if ART is stopped. Persistence has …
Cytomegalovirus-specific T-cell reconstitution following letermovir prophylaxis after hematopoietic cell transplantation
D Zamora, ER Duke, H Xie, BC Edmison… - Blood, The Journal …, 2021 - ashpublications.org
Decreased cytomegalovirus (CMV)-specific immunity after hematopoietic cell transplantation
(HCT) is associated with late CMV reactivation and increased mortality. Whether letermovir …
(HCT) is associated with late CMV reactivation and increased mortality. Whether letermovir …
Accumulation of phosphorus, dry matter and betaine during NaCl stress of split‐root citrus seedlings colonized with vesicular‐arbuscular mycorrhizal fungi on zero …
ER Duke, CR Johnson, KE Koch - New phytologist, 1986 - Wiley Online Library
Sodium chloride tolerance and phosphorus content were examined in split‐root Carrizo
citrange seedlings [Poncirus trifoliata (L.) Raf. ×Citrus sinensis (L.) Osbeck] colonized with a …
citrange seedlings [Poncirus trifoliata (L.) Raf. ×Citrus sinensis (L.) Osbeck] colonized with a …
[HTML][HTML] CMV viral load kinetics as surrogate endpoints after allogeneic transplantation
ER Duke, BD Williamson, B Borate… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND Viral load (VL) surrogate endpoints transformed development of HIV and
hepatitis C therapeutics. Surrogate endpoints for CMV-related morbidity and mortality could …
hepatitis C therapeutics. Surrogate endpoints for CMV-related morbidity and mortality could …
A Randomized Trial Evaluating the Prophylactic Activity of DSM265 Against Preerythrocytic Plasmodium falciparum Infection During Controlled Human Malarial …
SC Murphy, ER Duke, KJ Shipman… - The Journal of …, 2018 - academic.oup.com
… Elizabeth R Duke , Elizabeth R Duke … Sean C Murphy, Elizabeth R Duke, Kelly J Shipman,
Ryan L Jensen, Youyi Fong, Sue Ferguson, Holly E Janes, Kevin Gillespie, Annette M Seilie, …
Ryan L Jensen, Youyi Fong, Sue Ferguson, Holly E Janes, Kevin Gillespie, Annette M Seilie, …
[HTML][HTML] Cost-effectiveness analysis of molnupiravir versus best supportive care for the treatment of outpatient COVID-19 in adults in the US
…, A Alsumali, Y Jiang, M Schindler, ER Duke… - …, 2022 - Springer
Background and aims Coronavirus disease 2019 (COVID-19) imposes a substantial and
ongoing burden on the US healthcare system and society. Molnupiravir is a new oral antiviral …
ongoing burden on the US healthcare system and society. Molnupiravir is a new oral antiviral …