User profiles for E. Bartom
Elizabeth BartomNorthwestern University Verified email at northwestern.edu Cited by 4340 |
A beginner's guide to analysis of RNA sequencing data
… that neither of these scores pertains to the difference in gene expression levels, but instead
the scores describe the enrichment of genes in the target set within a given GO term (see E…
the scores describe the enrichment of genes in the target set within a given GO term (see E…
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span
…, S Berdnikovs, SM Bhorade, ET Bartom… - Journal of Experimental …, 2017 - rupress.org
Little is known about the relative importance of monocyte and tissue-resident macrophages
in the development of lung fibrosis. We show that specific genetic deletion of monocyte-…
in the development of lung fibrosis. We show that specific genetic deletion of monocyte-…
Early intensive behavioral intervention (EIBI) for young children with autism spectrum disorders (ASD)
Background The rising prevalence of autism spectrum disorders (ASD) increases the need
for evidence‐based behavioral treatments to lessen the impact of symptoms on children's …
for evidence‐based behavioral treatments to lessen the impact of symptoms on children's …
Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas
… (e) 5-d growth curve of SF8628 cells treated with JQ1 (300 nM concentration) and OTX015
(300 nM concentration), as compared to treatment with DMSO. The plot represents a crystal-…
(300 nM concentration), as compared to treatment with DMSO. The plot represents a crystal-…
[PDF][PDF] Cancer-associated IDH1 promotes growth and resistance to targeted therapies in the absence of mutation
…, FM Kouri, Y Bi, M Kachman, JL May, E Bartom… - Cell reports, 2017 - cell.com
Oncogenic mutations in two isocitrate dehydrogenase (IDH)-encoding genes (IDH1 and IDH2)
have been identified in acute myelogenous leukemia, low-grade glioma, and secondary …
have been identified in acute myelogenous leukemia, low-grade glioma, and secondary …
Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2
… STAT5 binds directly to E κi and can prevent the recruitment of E2A 16,19 . However, it is …
to E κi and enabled recruitment of the histone methyltransferase Ezh2 that decorated E κi , the J …
to E κi and enabled recruitment of the histone methyltransferase Ezh2 that decorated E κi , the J …
Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability
…, EJ Rendleman, SA Marshall, A Krueger, ET Bartom… - Nature …, 2017 - nature.com
… (e) The lethality of the trr null allele trr[1] can be rescued by various genomic trr constructs
containing the trr gene and putative regulatory regions. Only male rescued flies are shown. …
containing the trr gene and putative regulatory regions. Only male rescued flies are shown. …
CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia
Loss of chromosome 7 and del(7q) [−7/del(7q)] are recurring cytogenetic abnormalities in
hematologic malignancies, including acute myeloid leukemia and therapy-related myeloid …
hematologic malignancies, including acute myeloid leukemia and therapy-related myeloid …
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation
… e, GO terms for genes at least partially rescued following CXXC1 knockdown in MLL2-KO
mESCs compared to MLL2-KO mESCs. The P values were computed using Metascape, which …
mESCs compared to MLL2-KO mESCs. The P values were computed using Metascape, which …
[HTML][HTML] A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer
The N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) mouse model is an attractive model
system of muscle-invasive bladder cancer (MIBC) as it recapitulates the histology of human …
system of muscle-invasive bladder cancer (MIBC) as it recapitulates the histology of human …