User profiles for E. Bartom

Elizabeth Bartom

Northwestern University
Verified email at northwestern.edu
Cited by 4340

A beginner's guide to analysis of RNA sequencing data

…, A Bharat, KM Ridge, ET Bartom… - American journal of …, 2018 - atsjournals.org
… that neither of these scores pertains to the difference in gene expression levels, but instead
the scores describe the enrichment of genes in the target set within a given GO term (see E

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

…, S Berdnikovs, SM Bhorade, ET Bartom… - Journal of Experimental …, 2017 - rupress.org
Little is known about the relative importance of monocyte and tissue-resident macrophages
in the development of lung fibrosis. We show that specific genetic deletion of monocyte-…

Early intensive behavioral intervention (EIBI) for young children with autism spectrum disorders (ASD)

B Reichow, EE Barton, BA Boyd… - Cochrane database of …, 2012 - cochranelibrary.com
Background The rising prevalence of autism spectrum disorders (ASD) increases the need
for evidence‐based behavioral treatments to lessen the impact of symptoms on children's …

Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas

A Piunti, R Hashizume, MA Morgan, ET Bartom… - Nature medicine, 2017 - nature.com
… (e) 5-d growth curve of SF8628 cells treated with JQ1 (300 nM concentration) and OTX015
(300 nM concentration), as compared to treatment with DMSO. The plot represents a crystal-…

[PDF][PDF] Cancer-associated IDH1 promotes growth and resistance to targeted therapies in the absence of mutation

…, FM Kouri, Y Bi, M Kachman, JL May, E Bartom… - Cell reports, 2017 - cell.com
Oncogenic mutations in two isocitrate dehydrogenase (IDH)-encoding genes (IDH1 and IDH2)
have been identified in acute myelogenous leukemia, low-grade glioma, and secondary …

Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2

…, SE Powers, M Maienschein-Cline, ET Bartom… - Nature …, 2011 - nature.com
… STAT5 binds directly to E κi and can prevent the recruitment of E2A 16,19 . However, it is …
to E κi and enabled recruitment of the histone methyltransferase Ezh2 that decorated E κi , the J …

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability

…, EJ Rendleman, SA Marshall, A Krueger, ET Bartom… - Nature …, 2017 - nature.com
… (e) The lethality of the trr null allele trr[1] can be rescued by various genomic trr constructs
containing the trr gene and putative regulatory regions. Only male rescued flies are shown. …

CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia

…, CD Brown, X Wang, ET Bartom… - Blood, The Journal …, 2013 - ashpublications.org
Loss of chromosome 7 and del(7q) [−7/del(7q)] are recurring cytogenetic abnormalities in
hematologic malignancies, including acute myeloid leukemia and therapy-related myeloid …

Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation

…, Z Zhao, K Cao, MA Morgan, BD Singer, ET Bartom… - Nature …, 2020 - nature.com
e, GO terms for genes at least partially rescued following CXXC1 knockdown in MLL2-KO
mESCs compared to MLL2-KO mESCs. The P values were computed using Metascape, which …

[HTML][HTML] A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer

…, SE Crawford, D Hu, JD Licht, CK Collings, E Bartom… - Oncogene, 2018 - nature.com
The N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) mouse model is an attractive model
system of muscle-invasive bladder cancer (MIBC) as it recapitulates the histology of human …