User profiles for E. Segal

Eran Segal

Professor of Computer Science, Weizmann Institute of Science
Verified email at weizmann.ac.il
Cited by 69231

Role of the gut microbiota in nutrition and health

AM Valdes, J Walter, E Segal, TD Spector - Bmj, 2018 - bmj.com
… doi:10.3390/nu3060637 8 Levy M, Kolodziejczyk AA, Thaiss CA, Elinav E. Dysbiosis and
the immune system. Nat Rev Immunol 2017;17:219-32. … Code of Federal Regulations …

The pros, cons, and many unknowns of probiotics

J Suez, N Zmora, E Segal, E Elinav - Nature medicine, 2019 - nature.com
Consumption of over-the-counter probiotics for promotion of health and well-being has
increased worldwide in recent years. However, although probiotic use has been greatly …

Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

…, J Parkhill, J Raes, T Rattei, A Salonen, E Segal… - Nature, 2023 - nature.com
Whether the human fetus and the prenatal intrauterine environment (amniotic fluid and
placenta) are stably colonized by microbial communities in a healthy pregnancy remains a …

Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data

E Segal, M Shapira, A Regev, D Pe'er, D Botstein… - Nature …, 2003 - nature.com
Much of a cell's activity is organized as a network of interacting modules: sets of genes
coregulated to respond to different conditions. We present a probabilistic method for identifying …

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

…, S Yust-Katz, I Barshack, DS Peeper, DJ Raz, E Segal… - Science, 2020 - science.org
… (E) Box blot of the numbers of bacterial species present in each tumor. For (D) and (E), values
were calculated on rarefied data of 40 samples per tumor type, with 10 iterations. For each …

Beyond the imitation game: Quantifying and extrapolating the capabilities of language models

…, E Segal, E Hagerman, E Barnes, E Donoway… - arXiv preprint arXiv …, 2022 - arxiv.org
Language models demonstrate both quantitative improvement and new qualitative
capabilities with increasing scale. Despite their potentially transformative impact, these new …

[PDF][PDF] Personalized nutrition by prediction of glycemic responses

…, R Bikovsky, Z Halpern, E Elinav, E Segal - Cell, 2015 - cell.com
… We thank the Segal and Elinav group members for fruitful discussions; Keren Segal, Yuval
Dor, Tali Raveh-Sadka, Michal Levo, and Leeat Keren for fruitful discussions and critical …

Environment dominates over host genetics in shaping human gut microbiota

…, J Fu, C Wijmenga, A Zhernakova, E Elinav, E Segal - Nature, 2018 - nature.com
Human gut microbiome composition is shaped by multiple factors but the relative contribution
of host genetics remains elusive. Here we examine genotype and microbiome data from …

A module map showing conditional activity of expression modules in cancer

E Segal, N Friedman, D Koller, A Regev - Nature genetics, 2004 - nature.com
DNA microarrays are widely used to study changes in gene expression in tumors, but such
studies are typically system-specific and do not address the commonalities and variations …

[HTML][HTML] The DNA-encoded nucleosome organization of a eukaryotic genome

…, EM LeProust, TR Hughes, JD Lieb, J Widom, E Segal - Nature, 2009 - nature.com
e, Same as d, comparing our model predictions to the in vivo map. f, In vitro nucleosome
sequence preferences on yeast genomic DNA are predictive of the in vivo nucleosome …