The heart relies mainly on mitochondrial metabolism to provide the energy needed for
pumping blood to oxygenate the organs of the body. The study of mitochondrial function in the …

Obesity‐induced insulin resistance and type 2 diabetes mellitus can ultimately result in
various complications, including diabetic cardiomyopathy. In this case, cardiac dysfunction is …

HIF prolyl hydroxylases (PHD1–3) are oxygen sensors that regulate the stability of the
hypoxia-inducible factors (HIFs) in an oxygen-dependent manner. Here, we show that loss of …

Endogenous acetylcarnitine is an indicator of acetyl-CoA synthesized by multiple metabolic
pathways involving carbohydrates, amino acids, fatty acids, sterols, and ketone bodies, and …

The objective of this study was to determine the potential sites of maximal growth limitation
in Atlantic cod (Gadus morhua). Forty cod were reared in ten sea water tanks. Fish were …

Heart failure is a consequence of progressive deterioration of cardiac performance. Little is
known about the role of impaired oxidative phosphorylation in the progression of the disease, …

Background Mesenchymal stem cells (MSC) are self-renewing clonal progenitor cells of
nonhematopoietic tissues that exhibit a marked tropism to wounds and tumors. The authors' …

Fuel substrate supply and oxidative phosphorylation are key determinants of muscle
performance. Numerous studies of mammalian mitochondria are carried out (i) with substrate …

Changes in environmental temperature can pose considerable challenges to animals and
shifts in thermal habitat have been shown to be a major force driving species’ adaptation. …

… staining at 1 h of tunicamycin treatment (Figure 1D). Next, we confirmed that the induction
of the apoptotic CHOP did not occur at 1 h of tunicamycin treatment (Figure S1C). Thus, 1 h of …