User profiles for I. S. Gabashvili

Irene Gabashvili

Founder, Aurametrix
Verified email at aurametrix.com
Cited by 1754

[HTML][HTML] Solution structure of the E. coli 70S ribosome at 11.5 Å resolution

IS Gabashvili, RK Agrawal, CMT Spahn, RA Grassucci… - Cell, 2000 - cell.com
… of 16S RNA, which is involved in the association of the subunits, is displayed in red in top …
tRNA is shown in green. The arrangement of intersubunit bridges (open circles) is shown on …

[HTML][HTML] The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22

IS Gabashvili, ST Gregory, M Valle, R Grassucci… - Molecular cell, 2001 - cell.com
… While the purpose of the additional branches is unclear at this stage, it is possible that … In
contrast, the L22 mutant ribosome, which binds erythromycin but is not inhibited by it, had an …

The impact and applications of ChatGPT: a systematic review of literature reviews

IS Gabashvili - arXiv preprint arXiv:2305.18086, 2023 - arxiv.org
… The primary objective of this study is to evaluate the existing reviews and literature related
… where further research is needed. Another aim of this meta-review is to investigate methods …

[HTML][HTML] Ion channel gene expression in the inner ear

IS Gabashvili, BHA Sokolowski, CC Morton… - Journal of the …, 2007 - Springer
… We assume that there is experimental evidence supporting ion channel annotation if either
“… by our method is a smaller transcript than that previously reported in mouse. It is predicted to …

Escherichia coli 70 S ribosome at 15 Å resolution by cryo-electron microscopy: localization of fMet-tRNAfMet and fitting of L1 protein

…, P Penczek, RK Agrawal, IS Gabashvili… - Journal of molecular …, 1998 - Elsevier
… The large number of particles is required because the structure contains no symmetry that …
is instrumental in realizing the 14.9 Å resolution, we have indications that this improvement is

Movement of the decoding region of the 16 S ribosomal RNA accompanies tRNA translocation

MS VanLoock, RK Agrawal, IS Gabashvili, L Qi… - Journal of molecular …, 2000 - Elsevier
… The ribosome is the site of protein synthesis in the cell. In bacteria, it is composed of two
unequal subunits: the smaller 30 S subunit, which is responsible for decoding the messenger …

Dynamics of double stranded DNA reptation from bacteriophage

IS Gabashvili, AY Grosberg - Journal of Biomolecular Structure and …, 1992 - Taylor & Francis
is the friction of DNA segments in the whole globule volume, which is essential when the
globule decondensation is a … The third is the globule friction with the capsid inner surface, that is

[PDF][PDF] “Dumb” versus “smart” kinetochore models for chromosome congression during mitosis in vertebrate somatic cells

A Khodjakov, IS Gabashvili, CL Rieder - Cell motility and the cytoskeleton, 1999 - Citeseer
… In its best developed form, this hypothesis envisions that congression occurs because the
P force acting on each sister kinetochore is always on, that this P force is produced along the …

[HTML][HTML] Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA

IS Gabashvili, RK Agrawal, R Grassucci… - The EMBO …, 1999 - embopress.org
… The ribosome is a complex molecular machine of extraordinary precision that participates
in the synthesis of polypeptides in all organisms. The rRNA plays a central catalytic role (…

Structure and structural variations of the Escherichia coli 30 S ribosomal subunit as revealed by three-dimensional cryo-electron microscopy

IS Gabashvili, RK Agrawal, R Grassucci… - Journal of molecular …, 1999 - Elsevier
… procedure is possible whereby the conformational space is sampled by the use of different
initial reference structures. A subpopulation of particles whose structure is reflected best by a …