[HTML][HTML] A high-stringency blueprint of the human proteome
…, JC Waddington, JL Justice, J LaBaer… - Nature …, 2020 - nature.com
The Human Proteome Organization (HUPO) launched the Human Proteome Project (HPP)
in 2010, creating an international framework for global collaboration, data sharing, quality …
in 2010, creating an international framework for global collaboration, data sharing, quality …
The sentinel within: exploiting the immune system for cancer biomarkers
KS Anderson, J LaBaer - Journal of proteome research, 2005 - ACS Publications
The release of proteins from tumors triggers an immune response in cancer patients. These
tumor antigens arise from several mechanisms including tumor-specific alterations in protein …
tumor antigens arise from several mechanisms including tumor-specific alterations in protein …
Protein microarrays as tools for functional proteomics
J LaBaer, N Ramachandran - Current opinion in chemical biology, 2005 - Elsevier
Protein microarrays present an innovative and versatile approach to study protein abundance
and function at an unprecedented scale. Given the chemical and structural complexity of …
and function at an unprecedented scale. Given the chemical and structural complexity of …
α-Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
…, GA Caldwell, G Marsischky, RD Kolodner, J LaBaer… - Science, 2006 - science.org
Alpha-synuclein (αSyn) misfolding is associated with several devastating neurodegenerative
disorders, including Parkinson's disease (PD). In yeast cells and in neurons αSyn …
disorders, including Parkinson's disease (PD). In yeast cells and in neurons αSyn …
New functional activities for the p21 family of CDK inhibitors.
J LaBaer, MD Garrett, LF Stevenson… - Genes & …, 1997 - genesdev.cshlp.org
… Bartek (Danish Cancer Society, Copenhagen, Den mark); for pi6, mouse monoclonal
antibody JC6 was used and was a gift of J. Koh (… We are indebted to the kindness of J. Bartek, …
antibody JC6 was used and was a gift of J. Koh (… We are indebted to the kindness of J. Bartek, …
[HTML][HTML] Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children
High proportions of autistic children suffer from gastrointestinal (GI) disorders, implying a
link between autism and abnormalities in gut microbial functions. Increasing evidence from …
link between autism and abnormalities in gut microbial functions. Increasing evidence from …
Self-assembling protein microarrays
… We thank the following labs for allowing us to use their arrayers and scanners: J. Mekalanos's
lab at Harvard Medical … Kunkel's lab at Children's Hospital (J. Haslett, T. Burleson, and M. …
lab at Harvard Medical … Kunkel's lab at Children's Hospital (J. Haslett, T. Burleson, and M. …
High-resolution DNA-binding specificity analysis of yeast transcription factors
…, M Pacek, A Rolfs, T Murthy, J Labaer… - Genome …, 2009 - genome.cshlp.org
… Li for technical assistance with yeast experiments; J.-A. Kwon and J. Love for technical
assistance with Affymetrix gene expression profiling experiments; T. Gurbich for technical …
assistance with Affymetrix gene expression profiling experiments; T. Gurbich for technical …
Next-generation high-density self-assembling functional protein arrays
We developed a high-density self-assembling protein microarray, based on the nucleic acid
programmable protein array (NAPPA) concept, to display thousands of proteins that are …
programmable protein array (NAPPA) concept, to display thousands of proteins that are …
Protein microarray signature of autoantibody biomarkers for the early detection of breast cancer
…, J Marks, P Engstrom, J LaBaer - Journal of proteome …, 2011 - ACS Publications
Cancer patients spontaneously generate autoantibodies (AAb) to tumor-derived proteins.
To detect AAb, we have probed novel high-density custom protein microarrays (NAPPA) …
To detect AAb, we have probed novel high-density custom protein microarrays (NAPPA) …