Evidence from clinical and experimental studies indicates that macrophages promote solid-tumour
progression and metastasis. Macrophages are educated by the tumour …

The fly Drosophila melanogaster is one of the most intensively studied organisms in biology
and serves as a model system for the investigation of many developmental and cellular …

Macrophages within the tumor microenvironment facilitate angiogenesis and extracellular-matrix
breakdown and remodeling and promote tumor cell motility. Recent studies reveal that …

We describe some novel methods to compute the index of any integer relative to a given
primitive root of a prime p. Our first method avoids the use of stored tables and apparently …

1. Introduction. This paper is concerned with the problem of obtaining theoretical estimates
for the number of arithmetical operations required to factorize a large integer n or test it for …

There is persuasive clinical and experimental evidence that macrophages promote cancer
initiation and malignant progression. During tumor initiation, they create an inflammatory …

Metastasis is a multistage process that requires cancer cells to escape from the primary
tumour, survive in the circulation, seed at distant sites and grow. Each of these processes …

Motivation: Prior biological knowledge greatly facilitates the meaningful interpretation of
gene-expression data. Causal networks constructed from individual relationships curated from …

The tumor microenvironment is a complex ecology of cells that evolves with and provides
support to tumor cells during the transition to malignancy. Among the innate and adaptive …

Macrophages, the most plastic cells of the haematopoietic system, are found in all tissues
and show great functional diversity. They have roles in development, homeostasis, tissue …