Atypical oral Candida isolates were recovered from 60 HIV-infected and three HIV-negative
individuals. These organisms were germ-tube-positive and produced abundant …

In order to efficiently edit eukaryotic genomes, it is critical to test the impact of chromatin
dynamics on CRISPR/Cas9 function and develop strategies to adapt the system to eukaryotic …

Synthetic Biology promises low-cost, exponentially scalable products and global health
solutions in the form of self-replicating organisms, or “living devices.” As these promises are …

Candida species other than C. albicans have become a significant cause of infection in
humans. Several of the more commonly isolated of these species are less susceptible to …

To elucidate principles operating in native biological systems and to develop novel
biotechnologies, synthetic biology aims to build and integrate synthetic gene circuits within native …

Our nationwide network of BME women faculty collectively argue that racial funding disparity
by the National Institutes of Health (NIH) remains the most insidious barrier to success of …

We describe a polymerase chain reaction (PCR) based approach to the detection and
identification of pathogenic fungi which has potential for the diagnosis of systemic mycoses. …

Proteolysis by the ubiquitin-proteasome pathway appears to have a complex role in
synaptic plasticity, but its various functions remain to be elucidated. Using late phase long-term …

Quorum-sensing networks enable bacteria to sense and respond to chemical signals produced
by neighboring bacteria. They are widespread: over 100 morphologically and genetically …

Chromatin is a system of proteins and DNA that regulates chromosome organization and
gene expression in eukaryotes. Essential features that support these processes include …