An evolutionarily young defense metabolite influences the root growth of plants via the ancient TOR signaling pathway

FG Malinovsky, MLF Thomsen, SJ Nintemann, LM Jagd… - Elife, 2017 - elifesciences.org
10.7554/eLife.29353.001 To optimize fitness a plant should monitor its metabolism to
appropriately control growth and defense. Primary metabolism can be measured by the universally …

[HTML][HTML] Verification of CRISPR editing and finding transgenic inserts by Xdrop indirect sequence capture followed by short-and long-read sequencing

T Blondal, C Gamba, LM Jagd, L Su, D Demirov, S Guo… - Methods, 2021 - Elsevier
Validation of CRISPR-Cas9 editing typically explores the immediate vicinity of the gene
editing site and distal off-target sequences, which has led to the conclusion that CRISPR-Cas9 …

Comparison of the relative potential for epigenetic and genetic variation to contribute to trait stability

EST Aller, LM Jagd, DJ Kliebenstein… - G3: Genes, Genomes …, 2018 - academic.oup.com
The theoretical ability of epigenetic variation to influence the heritable variation of complex
traits is gaining traction in the study of adaptation. This theory posits that epigenetic marks …

[HTML][HTML] T-DNA characterization of genetically modified 3-R-gene late blight-resistant potato events with a novel procedure utilizing the Samplix Xdrop® enrichment …

KA Zarka, LM Jagd, DS Douches - Frontiers in Plant Science, 2024 - frontiersin.org
Before the commercialization of genetically modified crops, the events carrying the novel
DNA must be thoroughly evaluated for agronomic, nutritional, and molecular characteristics. …

[HTML][HTML] Deletion of biosynthetic genes, specific SNP patterns and differences in transcript accumulation cause variation in hydroxynitrile glucoside content in barley …

M Ehlert, LM Jagd, I Braumann, C Dockter, C Crocoll… - Scientific reports, 2019 - nature.com
Barley (Hordeum vulgare L.) produces five leucine-derived hydroxynitrile glucosides, potentially
involved in alleviating pathogen and environmental stresses. These compounds include …

[PDF][PDF] Revealing the structure of a biosynthetic gene cluster in a barley variety using Xdrop® and nanopore sequencing

LM Jagd, C Gamba, P Mouritzen, S ApS - samplix.com
… Lea Møller Jagd, Cristina Gamba, and Peter Mouritzen … Schneider, LM, et al. 2016. The
Cer-cqu gene cluster determines three key players in a β-diketone synthase polyketide …

[PDF][PDF] Localizing lentiviral transduction-inserted CAR cassettes in T cells using Xdrop®

LM Jagd, T Blondal, P Mouritzen, S Aps - crisprmedicinenews.com
Starting from just 10 ng of DNA, Xdrop reveals gene cassettes inserted using lentivirus and
other transduction systems.

[PDF][PDF] Closing gaps in the sequence of a biosynthetic gene cluster in a tomato variety using Xdrop®

LM Jagd, C Gamba, P Mouritzen, S ApS - samplix.com
Whole genome sequencing is not the ideal method to close gaps in gene cluster sequences.

[PDF][PDF] Verifying CRISPR editing with Xdrop® enables the detection of unintended off-target rearrangements

T Blondal, C Gamba, C Johnston, LM Jagd… - samplix.com
Conventional PCR screening for CRISPR–Cas9 editing can miss large deletions and
complex rearrangements.

[PDF][PDF] Comparison of the Relative Potential for Epigenetic and Genetic Variation To Contribute to

EST Aller, LM Jagd, DJ Kliebenstein - G3 (Bethesda, Md.), 8 (5), 2018 - core.ac.uk
The theoretical ability of epigenetic variation to influence the heritable variation of complex
traits is gaining traction in the study of adaptation. This theory posits that epigenetic marks …