It has been more than 30 years since the publication of the new head hypothesis, which
proposed that the vertebrate head is an evolutionary novelty resulting from the emergence of …

The experimental malleability and unique phylogenetic position of the sea squirt Ciona
intestinalis as part of the sister group to the vertebrates have helped establish these marine …

The vertebrate heart is formed from diverse embryonic territories, including the first and second
heart fields. The second heart field (SHF) gives rise to the right ventricle and outflow tract, …

… Only 6 years elapsed before work began in earnest on the third edition with two new coauthors,
Jolene Smyth and Leah Christian. The three of us had begun working together as a team …

… l, Normal BTNs as seen in 9 of 12 control embryos (overexpression of β-galactosidase instead).
Embryos in k, l … Di Gregorio and all members of the Christiaen and Meinertzhagen labs …

The CRISPR/Cas9 system has ushered in a new era of targeted genetic manipulations. Here,
we report the use of CRISPR/Cas9 to induce double-stranded breaks in the genome of the …

Comprehensive gene networks in Ciona intestinalis embryos provide a foundation for
characterizing complex developmental processes, such as the initial phases of chordate heart …

Gene regulatory networks direct the progressive determination of cell fate during embryogenesis,
but how they control cell behavior during morphogenesis remains largely elusive. Cell …

Cardiac cell specification and the genetic determinants that govern this process are highly
conserved among Chordates. Recent studies have established the importance of …

ANISEED ( www.aniseed.cnrs.fr ) is the main model organism database for tunicates, the
sister-group of vertebrates. This release gives access to annotated genomes, gene expression …