Clinical trials of novel therapeutics for Alzheimer’s Disease (AD) have consumed a large
amount of time and resources with largely negative results. Repurposing drugs already …

Despite objective responses to poly(ADP-ribose) polymerase (PARP) inhibition and
improvements in progression-free survival (PFS) compared to standard chemotherapy in patients …

Conglomerate crystallization is the spontaneous generation of individually enantioenriched
crystals from a nonenantioenriched material. This behavior is responsible for spontaneous …

The Cambridge Structural Database (CSD) is a collection of over one million experimental
three-dimensional structures obtained through crystallographic analyses. These structures …

Background Heterodera glycines, commonly referred to as the soybean cyst nematode (SCN),
is an obligatory and sedentary plant parasite that causes over a billion-dollar yield loss to …

Hypersensitivity vasculitis associated with propylthiouracil therapy is a well-documented
clinical entity. Although any organ system may be involved, it is most unusual for pulmonary …

Objective To review the potential health risks associated with bioengineered ocular surface
tissue, which serves as a bellwether for other tissues. Methods All clinical trials using …

Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children under
the age of 15. In addition to genetic aberrations, epigenetic modifications such as DNA …

Machine learning (ML) techniques are being used to detect increasing amounts of malware
and variants. Despite successful applications of ML, we hypothesize that the full potential of …

RNA sequencing (RNA-seq) is becoming a prevalent approach to quantify gene expression
and is expected to gain better insights into a number of biological and biomedical questions …