Multiple models of human metabolism have been reconstructed, but each represents only a
subset of our knowledge. Here we describe Recon 2, a community-driven, consensus '…

Escher is a web application for visualizing data on biological pathways. Three key features
make Escher a uniquely effective tool for pathway visualization. First, users can rapidly …

To the Editor—Reconstructing metabolic reaction networks enables the development of
testable hypotheses of an organism’s metabolism under different conditions 1. State-of-the-art …

Genome-scale metabolic models (GEMs) represent extensive knowledgebases that provide
a platform for model simulations and integrative analysis of omics data. This study …

… The majority of the metabolic engineering studies using omics data focus on common
biofuels that are produced natively (eg, ethanol, n-butanol or fatty acids) or on platform strains …

For over two decades the School for Peace at Neve Shalom/Wahat al‐Salam has been
bringing together Jews and Arabs for dialogue workshops. This article examines the unique …

Genome-scale metabolic models (GEMs) have been widely used for quantitative exploration
of the relation between genotype and phenotype. Streamlined integration of enzyme …

When conditions change, unicellular organisms rewire their metabolism to sustain cell
maintenance and cellular growth. Such rewiring may be understood as resource re-allocation …

Understanding individual variation is fundamental to personalized medicine. Yet interpreting
complex phenotype data, such as multi-compartment metabolomic profiles, in the context of …

Genetic variation is the motor of evolution and allows organisms to overcome the environmental
challenges they encounter. It can be both beneficial and harmful in the process of …