Modellers of biological, ecological, and environmental systems cannot take for granted the
maxim ‘simple means general means good'. We argue here that viewing simple models as …

The discovery of microRNAs (miRNAs) has added a new player to the regulation of gene
expression. With the increasing number of molecular species involved in gene regulatory …

… Wolkenhauer conceived the manuscript and drafted the first versions. All authors contributed
to … O.Wolkenhauer and SKGupta supervised projects that included the curation of content to …

We propose an innovative, integrated, cost-effective health system to combat major non-communicable
diseases (NCDs), including cardiovascular, chronic respiratory, metabolic, …

This paper proposes a new algorithm in the fuzzy-c-means family, which is designed to cluster
time-series and is particularly suited for short time-series and those with unevenly spaced …

With the availability of quantitative data on the transcriptome and proteome level, there is an
increasing interest in formal mathematical models of gene expression and regulation. …

Mathematical modeling and dynamic simulation of signal transduction pathways is a central
theme in systems biology and is increasingly attracting attention in the postgenomic era. The …

Disease progression describes the change of disease status over time as function of
disease process and treatment effects. The status of a subject, such as a patient, may be …

Researchers around the world join forces to reconstruct the molecular processes of the virus-
host interactions aiming to combat the cause of the ongoing pandemic.

Background Numerous centrality measures have been introduced to identify “central” nodes
in large networks. The availability of a wide range of measures for ranking influential nodes …