User profiles for P. Khade

Pranav M Khade

Postdoctoral Fellow at Genentech
Verified email at gene.com
Cited by 51

[HTML][HTML] A Bayesian machine learning approach for drug target identification using diverse data types

NS Madhukar, PK Khade, L Huang, K Gayvert… - Nature …, 2019 - nature.com
Drug target identification is a crucial step in development, yet is also among the most
complex. To address this, we develop BANDIT, a Bayesian machine-learning approach that …

[HTML][HTML] Functional role of the sarcin–ricin loop of the 23S rRNA in the elongation cycle of protein synthesis

X Shi, PK Khade, KY Sanbonmatsu… - Journal of molecular …, 2012 - Elsevier
… EF-G·GTP catalyzes the translocation of the peptidyl-tRNA from the A site to the P site and
the deacylated tRNA from the P site to the E site in the ribosome. The associated mRNA also …

[PDF][PDF] 3D chaotic functions for image encryption

PN Khade, M Narnaware - International journal of computer science issues …, 2012 - Citeseer
This paper proposes the chaotic encryption algorithm based on 3D logistic map, 3D Chebyshev
map, and 3D, 2D Arnolds cat map for color image encryption. Here the 2D Arnolds cat …

[HTML][HTML] Functional interactions by transfer RNAs in the ribosome

P Khade, S Joseph - FEBS letters, 2010 - Elsevier
… of P/E and A/P tRNAs with respect to the 30S subunit to form the E/E and P/P states. …
completed polypeptide attached to the tRNA in the P site. Peptide hydrolysis by RF1 or RF2 …

CUBOSOMES-A DRUG DELIVERY SYSTEM.

K Tilekar, P Khade, S Kakade… - … Chemical & Biological …, 2014 - search.ebscohost.com
Cubosomes are the square and rounded particles with internal cubic lattices visible. The
discovery of cubosomes is a unique story and spans the fields of food science, differential …

Messenger RNA interactions in the decoding center control the rate of translocation

PK Khade, S Joseph - Nature structural & molecular biology, 2011 - nature.com
During protein synthesis, mRNA and tRNAs are iteratively translocated by the ribosome.
Precisely what molecular event is rate limiting for translocation is not known. Here we show that …

Perioperative implications and management of dextrocardia

Y Rapoport, CJ Fox, P Khade, ME Fox, RD Urman… - Journal of …, 2015 - Springer
… the P wave is now inverted. This means that there is a negative P wave in leads I and aVl,
and a positive P … In situs ambiguous and right isomerism, different origins of P waves may be …

What is the utility of postoperative antihelminthic therapy after resection for intraventricular neurocysticercosis?

P Khade, RS Lemos, LG Toussaint - World neurosurgery, 2013 - Elsevier
BACKGROUND: Neurocysticercosis (NCC) is the most common worldwide parasitic infection
of the central nervous system, and ventricular cysts are particularly problematic, carrying …

Characterizing and predicting protein hinges for mechanistic insight

PM Khade, A Kumar, RL Jernigan - Journal of molecular biology, 2020 - Elsevier
… Figure D) shows that the p-values remain similar for most values of alpha. The spike in p-…
Here p-value of 0 indicates that out of 10,000 permutations, the approach found no cases of the …

A copper composite embedded in graphene oxide as an efficient mordant to enhance the properties of natural dyes for cotton fabric

P Khade, M Bhakare, K Lokhande, S Some - ChemistrySelect, 2023 - Wiley Online Library
Synthetic dyes used in the textile sector have adverse impacts on the environment and human
health. Natural dyes are thus a suitable alternative for sustainable textile manufacturing …