User profiles for R. K. Smith-Bolton
Rachel Smith-BoltonAssociate Professor, University of Illinois Urbana-Champaign Verified email at illinois.edu Cited by 730 |
[PDF][PDF] Regenerative growth in Drosophila imaginal discs is regulated by Wingless and Myc
The study of regeneration would be aided greatly by systems that support large-scale
genetic screens. Here we describe a nonsurgical method for inducing tissue damage and …
genetic screens. Here we describe a nonsurgical method for inducing tissue damage and …
[HTML][HTML] The Drosophila Duox maturation factor is a key component of a positive feedback loop that sustains regeneration signaling
Regenerating tissue must initiate the signaling that drives regenerative growth, and sustain
that signaling long enough for regeneration to complete. How these key signals are …
that signaling long enough for regeneration to complete. How these key signals are …
Sprouty proteins are in vivo targets of Corkscrew/SHP-2 tyrosine phosphatases
…, SJ Toering, MA Simon, MA Krasnow, RK Smith-Bolton - 2006 - journals.biologists.com
Drosophila Corkscrew protein and its vertebrate ortholog SHP-2(now known as Ptpn11)
positively modulate receptor tyrosine kinase (RTK)signaling during development, but how these …
positively modulate receptor tyrosine kinase (RTK)signaling during development, but how these …
Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the Drosophila melanogaster Wing Imaginal Disc
AR Brock, M Seto, RK Smith-Bolton - Genetics, 2017 - academic.oup.com
Regeneration is a complex process that requires an organism to recognize and repair tissue
damage, as well as grow and pattern new tissue. Here, we describe a genetic screen to …
damage, as well as grow and pattern new tissue. Here, we describe a genetic screen to …
[PDF][PDF] Taranis protects regenerating tissue from fate changes induced by the wound response in Drosophila
KJ Schuster, RK Smith-Bolton - Developmental cell, 2015 - cell.com
… Schuster and Smith-Bolton have identified a gene, taranis, that protects regenerating
tissue from unwanted side effects of the signaling that drives wound closure and regenerative …
tissue from unwanted side effects of the signaling that drives wound closure and regenerative …
Trithorax regulates systemic signaling during Drosophila imaginal disc regeneration
A Skinner, SJ Khan, RK Smith-Bolton - Development, 2015 - journals.biologists.com
Although tissue regeneration has been studied in a variety of organisms, from Hydra to humans,
many of the genes that regulate the ability of each animal to regenerate remain unknown…
many of the genes that regulate the ability of each animal to regenerate remain unknown…
Regulation of growth and cell fate during tissue regeneration by the two SWI/SNF chromatin-remodeling complexes of Drosophila
Y Tian, RK Smith-Bolton - Genetics, 2021 - academic.oup.com
To regenerate, damaged tissue must heal the wound, regrow to the proper size, replace the
correct cell types, and return to the normal gene-expression program. However, the …
correct cell types, and return to the normal gene-expression program. However, the …
A rapid, gentle and scalable method for dissociation and fluorescent sorting of imaginal disc cells for mRNA sequencing
Dissociation of imaginal disc cells has been carried out previously to enable flow cytometry
and cell sorting to analyze cell cycle progression, cell size, gene expression, and other …
and cell sorting to analyze cell cycle progression, cell size, gene expression, and other …
Regeneration in crustaceans and insects
Many animal species have the capability to regenerate lost body parts. How regeneration
takes place and why animals have varying potentials for regeneration remain active questions …
takes place and why animals have varying potentials for regeneration remain active questions …
A Positive Feedback Loop Ensures Propagation of ROS Production and JNK Signaling Throughout Drosophila Tissue Regeneration
…, A Skinner, Y Tian, RK Smith-Bolton - bioRxiv, 2017 - biorxiv.org
Regenerating tissue must initiate the signaling that drives regenerative growth, and sustain
that signaling long enough for regeneration to complete. How these key signals are …
that signaling long enough for regeneration to complete. How these key signals are …