User profiles for R. Chammas
Roger ChammasCenter for Translational Research in Oncology, ICESP, Faculdade de Medicina da USP Verified email at usp.br Cited by 7888 |
[HTML][HTML] Phosphatidylcholine-derived lipid mediators: The crosstalk between cancer cells and immune cells
…, LNS Andrade, SO Bustos, R Chammas - Frontiers in …, 2022 - frontiersin.org
To become resistant, cancer cells need to activate and maintain molecular defense
mechanisms that depend on an energy trade-off between resistance and essential functions. …
mechanisms that depend on an energy trade-off between resistance and essential functions. …
Emerging technologies in extracellular vesicle-based molecular diagnostics
…, ML Samuels, MF Chou, R Chammas… - Expert review of …, 2014 - Taylor & Francis
Extracellular vesicles (EVs), including exosomes and microvesicles, have been shown to carry
a variety of biomacromolecules including mRNA, microRNA and other non-coding RNAs. …
a variety of biomacromolecules including mRNA, microRNA and other non-coding RNAs. …
[HTML][HTML] The role of kinin receptors in cancer and therapeutic opportunities
PLN da Costa, P Sirois, IF Tannock, R Chammas - Cancer letters, 2014 - Elsevier
… Our results show that treatment of mice bearing EMT6 sarcoma with the B1R antagonists
R-954 and R-715 resulted in enhanced doxorubicin penetration after 2 h of treatment (Fig. 3). …
R-954 and R-715 resulted in enhanced doxorubicin penetration after 2 h of treatment (Fig. 3). …
[HTML][HTML] Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner
Exposure of phosphatidylserine (PS) on cellular membranes and membrane-derived
microvesicles stimulates a number of anti-inflammatory responses involved in malignant processes…
microvesicles stimulates a number of anti-inflammatory responses involved in malignant processes…
[HTML][HTML] Sialylation of β1 integrins blocks cell adhesion to galectin-3 and protects cells against galectin-3-induced apoptosis
Y Zhuo, R Chammas, SL Bellis - Journal of biological chemistry, 2008 - ASBMB
In previous studies, we determined that β1 integrins from human colon tumors have elevated
levels of α2-6 sialylation, a modification added by β-galactosamide α-2,6-sialyltranferase I (…
levels of α2-6 sialylation, a modification added by β-galactosamide α-2,6-sialyltranferase I (…
Toxoplasma gondii infection reveals a novel regulatory role for galectin-3 in the interface of innate and adaptive immunity
In attempts to investigate the role of galectin-3 in innate immunity, we studied galectin-3-deficient
(gal3 −/− ) mice with regard to their response to Toxoplasma gondii infection, which is …
(gal3 −/− ) mice with regard to their response to Toxoplasma gondii infection, which is …
[HTML][HTML] Galectin-3 determines tumor cell adaptive strategies in stressed tumor microenvironments
…, LNDS Andrade, SO Bustos, R Chammas - Frontiers in …, 2016 - frontiersin.org
Galectin-3 is a member of the β-galactoside-binding lectin family, whose expression is often
dysregulated in cancers. While galectin-3 is usually an intracellular protein found in the …
dysregulated in cancers. While galectin-3 is usually an intracellular protein found in the …
RNA–DNA fibers and polygons with controlled immunorecognition activate RNAi, FRET and transcriptional regulation of NF-κB in human cells
Nucleic acid–based assemblies that interact with each other and further communicate with
the cellular machinery in a controlled manner represent a new class of reconfigurable …
the cellular machinery in a controlled manner represent a new class of reconfigurable …
The behaviour of masonry walls subjected to fire: Modelling and parametrical studies in the case of hollow burnt-clay bricks
… The load-bearing duration R is the elapsed time for which the wall continues to maintain its
… , ie the load-bearing criterion R is always satisfied for the wall studied in the present paper. …
… , ie the load-bearing criterion R is always satisfied for the wall studied in the present paper. …
[HTML][HTML] Emerging autophagy functions shape the tumor microenvironment and play a role in cancer progression-implications for cancer therapy
The tumor microenvironment (TME) is a complex environment where cancer cells reside
and interact with different types of cells, secreted factors, and the extracellular matrix. …
and interact with different types of cells, secreted factors, and the extracellular matrix. …