[HTML][HTML] The molecular motor toolbox for intracellular transport
RD Vale - Cell, 2003 - cell.com
Eukaryotic cells create internal order by using protein motors to transport molecules and
organelles along cytoskeletal tracks. Recent genomic and functional studies suggest that five …
organelles along cytoskeletal tracks. Recent genomic and functional studies suggest that five …
The way things move: looking under the hood of molecular motor proteins
RD Vale, RA Milligan - Science, 2000 - science.org
The microtubule-based kinesin motors and actin-based myosin motors generate motions
associated with intracellular trafficking, cell division, and muscle contraction. Early studies …
associated with intracellular trafficking, cell division, and muscle contraction. Early studies …
Phase separation of signaling molecules promotes T cell receptor signal transduction
… Zeng, and members from the Vale Laboratory for comments on this manuscript. This work
was supported by the HHMI’s Collaborative Innovation Awards, NIH (R01-GM56322 to MKR), …
was supported by the HHMI’s Collaborative Innovation Awards, NIH (R01-GM56322 to MKR), …
Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility
RD Vale, TS Reese, MP Sheetz - Cell, 1985 - cell.com
Axoplasm from the squid giant axon contains a soluble protein translocator that induces
movement of microtubules on glass, latex beads on microtubules, and axoplasmic organelles on …
movement of microtubules on glass, latex beads on microtubules, and axoplasmic organelles on …
[HTML][HTML] Advanced methods of microscope control using μManager software
…, N Amodaj, H Pinkard, RD Vale… - Journal of biological …, 2014 - ncbi.nlm.nih.gov
μManager is an open-source, cross-platform desktop application, to control a wide variety of
motorized microscopes, scientific cameras, stages, illuminators, and other microscope …
motorized microscopes, scientific cameras, stages, illuminators, and other microscope …
Kinesin walks hand-over-hand
Kinesin is a processive motor that takes 8.3-nm center-of-mass steps along microtubules for
each adenosine triphosphate hydrolyzed. Whether kinesin moves by a “hand-over-hand” or …
each adenosine triphosphate hydrolyzed. Whether kinesin moves by a “hand-over-hand” or …
[PDF][PDF] A protein-tagging system for signal amplification in gene expression and fluorescence imaging
Signals in many biological processes can be amplified by recruiting multiple copies of
regulatory proteins to a site of action. Harnessing this principle, we have developed a protein …
regulatory proteins to a site of action. Harnessing this principle, we have developed a protein …
Computer control of microscopes using µManager
…, N Amodaj, K Hoover, R Vale… - Current protocols in …, 2010 - Wiley Online Library
… Since 2005, several members of Ron Vale's laboratory at UCSF, with the assistance of
contributors worldwide, have been developing µManager: a free, open-source software package …
contributors worldwide, have been developing µManager: a free, open-source software package …
T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition
… We acknowledge R. Ahmed, A. Kamphorst, and membersof the Vale laboratory for comments
and discussions. RDVis an investigator of the Howard Hughes Medical Institute. DKS was …
and discussions. RDVis an investigator of the Howard Hughes Medical Institute. DKS was …
A standardized kinesin nomenclature
…, WM Saxton, M Schliwa, JM Scholey, RD Vale… - The Journal of cell …, 2004 - rupress.org
In recent years the kinesin superfamily has become so large that several different naming
schemes have emerged, leading to confusion and miscommunication. Here, we set forth a …
schemes have emerged, leading to confusion and miscommunication. Here, we set forth a …