Infection with Asian-lineage Zika virus (ZIKV) has been associated with Guillain–Barré
syndrome and fetal abnormalities, but the underlying mechanisms remain poorly understood. …

BACKGROUND: Accurate assessment of medication adherence has been difficult to achieve
but is essential to drug evaluation in clinical trials and improved outcomes in clinical care. …

We report the isolation and characterization of a spontaneously immortalized human keratinocyte
cell line, NIKS. The cell line is not tumorigenic in athymic nude mice and maintains cell-…

Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …

Objective: Resting CD4+ T cells have been recognized as the major cell reservoir of latent
HIV-1 during antiretroviral therapy (ART). Using an simian immunodeficiency virus (SIV)/…

The spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
plays a key role in viral infectivity. It is also the major antigen stimulating the host's protective …

Background Zika virus (ZIKV; Flaviviridae, Flavivirus) was declared a public health emergency
of international concern by the World Health Organization (WHO) in February 2016, …

Bortezomib (Velcade/PS341), a proteasome inhibitor used in the treatment of multiple myeloma
(MM), can inhibit activation of nuclear factor-κB (NF-κB), a family of transcription factors …

An estimated 50–90% of individuals with cocaine use disorder (CUD) also report using
alcohol. Cocaine users report coabusing alcohol to ‘self-medicate’ against the negative …

Nonhuman primates are widely used to study correlates of protective immunity in AIDS
research. Successful cellular immune responses have been difficult to identify because …