Although the risks of developing chronic diseases are attributed to both genetic and environmental
factors, 70 to 90% of disease risks are probably due to differences in environments ( …

Benzene is known to have toxic effects on the blood and bone marrow, but its impact at
levels below the US occupational standard of 1 part per million (ppm) remains uncertain. In a …

During the 1920s, the forerunners of exposure science collaborated with health professionals
to investigate the causes of occupational diseases. With the birth of US regulatory …

The food metabolome is defined as the part of the human metabolome directly derived from
the digestion and biotransformation of foods and their constituents. With >25,000 …

… Details of our applications of these procedures are also described elsewhere (RAPPAPORT
et al., in preparation). Two of the authors (H. Kromhout and SM Rappaport) independently …

The attack on the World Trade Center (WTC) created an acute environmental disaster of
enormous magnitude. This study characterizes the environmental exposures resulting from …

… unexplored means for interrogating biologically relevant exposures (Rappaport 2012). … in
blood from disease cases and controls (Rappaport 2012). Internal measures of exposure, such …

Because airborne exposure varies greatly over time and between individual workers,
occupational hygienists should adopt sampling strategies which recognize the inherent statistical …

The risk of acquiring a chronic disease is influenced by a person’s genetics (G) and exposures
received during life (the ‘exposome’, E) plus their interactions (G×E). Yet, investigators …

The exposome is defined as the totality of all human environmental exposures from
conception to death. It is often regarded as the complement to the genome, with the interaction …