User profiles for S. P. Preston

Simon Preston

- Verified email at wehi.edu.au - Cited by 3424

Simon Preston

- Verified email at nottingham.ac.uk - Cited by 1063

[HTML][HTML] IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology

M Pellegrini, T Calzascia, JG Toe, SP Preston, AE Lin… - Cell, 2011 - cell.com
Understanding the factors that impede immune responses to persistent viruses is essential
in designing therapies for HIV infection. Mice infected with LCMV clone-13 have persistent …

[PDF][PDF] Severe malaria infections impair germinal center responses by inhibiting T follicular helper cell differentiation

…, A Ly, CY Chiu, J Tellier, DL Hill, SP Preston… - Cell reports, 2016 - cell.com
Naturally acquired immunity to malaria develops only after years of repeated exposure to
Plasmodium parasites. Despite the key role antibodies play in protection, the cellular …

[PDF][PDF] SIDT2 transports extracellular dsRNA into the cytoplasm for innate immune recognition

…, KD Elgass, AS Weisman, PJ Baker, SP Preston… - Immunity, 2017 - cell.com
Double-stranded RNA (dsRNA) is a common by-product of viral infections and acts as a
potent trigger of antiviral immunity. In the nematode C. elegans, sid-1 encodes a dsRNA …

[PDF][PDF] Macrophage and neutrophil death programs differentially confer resistance to tuberculosis

MD Stutz, CC Allison, S Ojaimi, SP Preston… - Immunity, 2021 - cell.com
Apoptosis can potently defend against intracellular pathogens by directly killing microbes
and eliminating their replicative niche. However, the reported ability of Mycobacterium …

[HTML][HTML] Process parameter optimisation of laser clad iron based alloy: Predictive models of deposition efficiency, porosity and dilution

L Reddy, SP Preston, PH Shipway, C Davis… - Surface and Coatings …, 2018 - Elsevier
As a candidate coating material for heat-exchanger surfaces in commercial power generation
boiler, an amorphous/glass forming Fe-Cr-B alloy NanoSteel SHS 7170 was deposited by …

Exploiting heterogeneous environments: does photosynthetic acclimation optimize carbon gain in fluctuating light?

…, OE Jensen, GN Johnson, SP Preston… - Journal of …, 2015 - academic.oup.com
Plants have evolved complex mechanisms to balance the efficient use of absorbed light
energy in photosynthesis with the capacity to use that energy in assimilation, so avoiding …

[HTML][HTML] Epigenetic silencing of RIPK3 in hepatocytes prevents MLKL-mediated necroptosis from contributing to liver pathologies

SP Preston, MD Stutz, CC Allison, U Nachbur, Q Gouil… - Gastroenterology, 2022 - Elsevier
Background & Aims Necroptosis is a highly inflammatory mode of cell death that has been
implicated in causing hepatic injury including steatohepatitis/ nonalcoholic steatohepatitis (…

[HTML][HTML] Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways

…, KJ Henley, RM Lane, D Moujalled, SP Preston… - Nature …, 2014 - nature.com
BH3 mimetic drugs that target BCL-2 family pro-survival proteins to induce tumour cell
apoptosis represent a new era in cancer therapy. Clinical trials of navitoclax (ABT-263, which …

[HTML][HTML] The 4-dimensional plant: effects of wind-induced canopy movement on light fluctuations and photosynthesis

AJ Burgess, R Retkute, SP Preston… - Frontiers in plant …, 2016 - frontiersin.org
Physical perturbation of a plant canopy brought about by wind is a ubiquitous phenomenon
and yet its biological importance has often been overlooked. This is partly due to the …

[BOOK][B] The battle of Crécy, 1346

A Ayton, SP Preston - 2002 - degruyter.com
Preston Sir Philip : Sir Philip Preston is an independent scholar, and founding secretary of
the Battle of Crécy Trust, which is dedicated to research into the battle and all matters relating …