… If you wish to reuse any or all of this article please use the link below which will take you to
the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and …

… phenotypes such as adult-onset Still’s disease 149 . A seronegative refractory RA more akin
to autoinflammatory conditions or adult-onset Still’s disease could be a future candidate for …

… This may suggest other autoimmune responses other than ACPA contributes to ACPA-…
(5) Finally, a coding variant in a non-classical HLA gene (HLA-DOA) that alters the gene’s …

A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated
variants with diverse genomic and biological data sets to provide insight into …

To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …

Using the Immunochip custom SNP array, which was designed for dense genotyping of 186
loci identified through genome-wide association studies (GWAS), we analyzed 11,475 …

Generalised osteoporosis is a feature of established rheumatoid arthritis but whether this is
a consequence of treatment, immobility, or disease activity has been unclear. We estimated …

The major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility
to more common diseases than any other region of the human genome, including almost …

Smoking is a leading global cause of disease and mortality 1 . We established the Oxford-GlaxoSmithKline
study (Ox-GSK) to perform a genome-wide meta-analysis of SNP association …

We used the Immunochip array to analyze 2,816 individuals with juvenile idiopathic arthritis
(JIA), comprising the most common subtypes (oligoarticular and rheumatoid factor–negative …