[HTML][HTML] Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway
CA Lovejoy, W Li, S Reisenweber, S Thongthip… - PLoS …, 2012 - journals.plos.org
… As the ALT lines were expected to have an impaired G1/S DNA damage checkpoint due
to their p53 deficiency, we focused our efforts on the G2/M checkpoint. Entry into mitosis is …
to their p53 deficiency, we focused our efforts on the G2/M checkpoint. Entry into mitosis is …
FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair
…, HY Gee, AK Ghosh, S Natarajan, S Thongthip… - Nature …, 2012 - nature.com
Chronic kidney disease (CKD) represents a major health burden 1 . Its central feature of renal
fibrosis is not well understood. By exome sequencing, we identified mutations in FAN1 as …
fibrosis is not well understood. By exome sequencing, we identified mutations in FAN1 as …
Glutathione and its antiaging and antimelanogenic effects
S Weschawalit, S Thongthip, P Phutrakool… - Clinical, cosmetic and …, 2017 - Taylor & Francis
… properties on melanogenesis and antioxidants in general are protective against aging
process, the “dual” antimelanogenic and antiaging properties demonstrated in Watanabe’s and …
process, the “dual” antimelanogenic and antiaging properties demonstrated in Watanabe’s and …
Massively parallel sequencing, aCGH, and RNA-Seq technologies provide a comprehensive molecular diagnosis of Fanconi anemia
…, E Flynn, SK Sen, S Thongthip… - Blood, The Journal …, 2013 - ashpublications.org
… Fibroblast and LCL cell lines were grown in Dulbecco’s modified Eagle’s medium (with 15%
fetal bovine serum) and RPMI 1640 (with 20% fetal bovine serum) media, respectively. Both …
fetal bovine serum) and RPMI 1640 (with 20% fetal bovine serum) media, respectively. Both …
Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction
S Thongthip, M Bellani, SQ Gregg… - Genes & …, 2016 - genesdev.cshlp.org
… -deficient MEFs did not show hypersensitivity to either camptothecin (CPT) or hydroxyurea
(HU), suggesting that FAN1 is specifically required for the repair of DNA ICLs and not other S-…
(HU), suggesting that FAN1 is specifically required for the repair of DNA ICLs and not other S-…
Influence of air pollution and meteorological factors on the spread of COVID-19 in the Bangkok Metropolitan Region and air quality during the outbreak
… This study found that RH (%), AH (g/m 3 ) and WS (m/s) had a positive association with the
number of COVID-19 cases that was statistically significant showed positive associations with …
number of COVID-19 cases that was statistically significant showed positive associations with …
[PDF][PDF] Human health risk assessment of PM2. 5-bound heavy metal of anthropogenic sources in the Khon Kaen Province of Northeast Thailand
…, S Daduang, T Tessiri, J Rayubkul, S Thongtip… - Heliyon, 2022 - cell.com
… For instance, some major elements connected with PM2.5 measured in this study (Pb, Cd,
Cu, or Mn), are found to be emissions from debris of wearing of tyres and old’s automobile …
Cu, or Mn), are found to be emissions from debris of wearing of tyres and old’s automobile …
[HTML][HTML] Relationships between genome-wide R-loop distribution and classes of recurrent DNA breaks in neural stem/progenitor cells
S Thongthip, A Carlson, MP Crossley, B Schwer - Scientific reports, 2022 - nature.com
… P values were determined by one-way ANOVA with Tukey’s post hoc correction for multiple
comparisons. (E) Left, metaplot analysis of RPKM-normalized, raw DRIP-seq signal across …
comparisons. (E) Left, metaplot analysis of RPKM-normalized, raw DRIP-seq signal across …
Suppression of non-homologous end joining does not rescue DNA repair defects in Fanconi anemia patient cells
… However, we note that slow-growing cells often appear resistant to drugs like MMC that act
in S phase, so any growth differences between cell lines may lead to differential sensitivity to …
in S phase, so any growth differences between cell lines may lead to differential sensitivity to …
[PDF][PDF] An increase in urinary primaquine and a reduction in urinary primaquine-5, 6-orthoquinone in the Thai population with CYP2D6 reduced enzyme function
W Pookmanee, S Thongthip, M Mungthin, C Sukasem… - Heliyon, 2024 - cell.com
Objectives Primaquine is metabolized by the cytochrome P450-2D6 enzyme (CYP2D6) to
an active primaquine-5,6-orthoquinone (POQ). No relationships of CYP2D6 polymorphisms …
an active primaquine-5,6-orthoquinone (POQ). No relationships of CYP2D6 polymorphisms …