The technical challenges and motivations for high-energy, short-pulse generation with the
National Ignition Facility (NIF) and possibly other large-scale Nd: glass lasers are reviewed. …

There is a need for new therapeutic targets with which to prevent Alzheimer’s disease (AD),
a major contributor to aging-related cognitive decline. Here we report the construction and …

Suz12 is a component of the Polycomb group complexes 2, 3, and 4 (PRC 2/3/4). These
complexes are critical for proper embryonic development, but very few target genes have been …

Methylation of DNA in combination with histone modifications establishes an epigenetic
code that ensures the proper control of gene expression. Although DNA methyltransferases …

Magnetic field and angle dependences of the critical current density J c (H, θ) in epitaxial c-oriented
Y Ba 2 Cu 3 O 7− δ thin films are measured by the four-probe transport current …

Biological functions are carried out by groups of interacting molecules, cells or tissues,
known as communities. Membership in these communities may overlap when biological …

Existing Petawatt class lasers today based on Nd:glass architectures operating at nominally
500 J, 0.5 ps use meter-scale aperture, gold-overcoated master photoresist gratings to …

We present theoretical and experimental evidence that nonionizing prepulses with intensities
as low as 10 8–10 9 W/cm 2 can substantially alter high intensity laser-solid interactions. …

We report on the results from several of our alkali laser systems. We show highly efficient
performance from an alexandrite-pumped rubidium laser. Using a laser diode stack as a pump …

The interaction of intense, ultra-short laser pulses (USLP) with a surface of transparent
dielectrics is considered. The combination of multi-photon absorption and impact ionization …