Background:An improved understanding of the contribution of the diet to health and disease
risks requires accurate assessments of dietary exposure in nutritional epidemiologic studies…

Introduction For pediatric diseases like childhood leukemia, a short latency period points to
in-utero exposures as potentially important risk factors. Untargeted metabolomics of small …

Consumption of cruciferous vegetables (CVs) is inversely correlated to many human
diseases including cancer (breast, lung, and bladder), diabetes, and cardiovascular and …

Early-life exposures are believed to influence the incidence of pediatric acute lymphoblastic
leukemia (ALL). Archived neonatal blood spots (NBS), collected within the first days of life, …

An important but understudied class of human exposures is comprised of reactive electrophiles
that cannot be measured in vivo because they are short-lived. An avenue for assessing …

Extraction of meaningful biological information from urinary metabolomic profiles obtained
by liquid-chromatography coupled to mass spectrometry (MS) necessitates the control of …

Many vegetables considered beneficial to human health contain the amino acid derivative, S-methyl-l-cysteine
sulphoxide. This plant secondary metabolite functions as a phytoalexin …

Although benzene has long been recognized as a cause of human leukemia, the mechanism
by which this simple molecule causes cancer has been problematic. A complicating factor …

The developing fetus is exposed to chemicals, which are metabolized to electrophiles that
form adducts with nucleophilic Cys34 of human serum albumin (HSA). By measuring these …

Background Epidemiologists are beginning to employ metabolomics and lipidomics with
archived blood from incident cases and controls to discover causes of cancer. Although several …